Pain relief showdown: ketamine vs lidocaine after surgery
NCT ID NCT07248384
First seen Jan 09, 2026 · Last updated Jun 22, 2026 · Updated 26 times
Summary
This study tested two common painkillers, ketamine and lidocaine, to see which works better for pain after gallbladder removal. 76 adults were randomly assigned to receive one of the drugs right after surgery. Researchers measured their pain levels over the next 24 hours. The goal is to find a better way to manage post-surgery pain.
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the original study
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Contacts and locations
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Locations
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Liaquat National Hospital, Anesthesiology Department
Karachi, Sindh, 74800, Pakistan
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
Active substance
ketamine and lidocaine (given as single IV injections after surgery)
What this could lead to
If one drug works better, it could offer a simple, low-cost way to ease pain after gallbladder surgery.
What could go wrong
This is a small, early-phase trial with only 76 people. Results may not apply to other surgeries or patients, and both drugs have side effects like dizziness or nausea.
Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.