Ketamine showdown: IV drip vs nasal spray for depression
NCT ID NCT06713616
First seen Feb 21, 2026 · Last updated May 22, 2026 · Updated 14 times
Summary
This study compares two forms of ketamine—one given through an IV and the other as a nasal spray—to see which works better for people with depression that hasn't improved with other treatments. About 400 adults with moderate to severe depression will receive either treatment for one month. Researchers will track how well symptoms improve, how acceptable the treatment feels, and any side effects.
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Study contacts
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Contact
Phone: •••-•••-•••• Email: •••••@•••••
Locations
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Emory University
RECRUITINGAtlanta, Georgia, 30322, United States
Contact Phone: •••-•••-••••
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Houston Center for Advanced Psychiatric Treatment
RECRUITINGBellaire, Texas, 77401, United States
Contact
Contact
Contact Phone: •••-•••-•••• Email: •••••@•••••
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LifeStance Health
RECRUITINGMoore, Oklahoma, 73160, United States
Contact Email: •••••@•••••
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Mood Institute
RECRUITINGMilford, Connecticut, 06461, United States
Contact Phone: •••-•••-•••• Email: •••••@•••••
Contact
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University of Michigan
ACTIVE_NOT_RECRUITINGAnn Arbor, Michigan, 48104, United States
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Yale School of Medicine
RECRUITINGNew Haven, Connecticut, 06512, United States
Contact Phone: •••-•••-•••• Email: •••••@•••••
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