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Ketamine tested to stop chronic pain after mastectomy

NCT ID NCT05037123

First seen May 18, 2026 · Last updated May 20, 2026 · Updated 1 time

Summary

This study tests whether giving ketamine during or after breast surgery can lower the chance of long-term pain. About 765 women having mastectomy will get a low-dose ketamine infusion or a placebo (salt water). The goal is to see if ketamine helps reduce pain severity and interference with daily life over time.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Locations

  • Brigham and Women's Hospital - Harvard University

    Chestnut Hill, Massachusetts, 02467, United States

  • Mayo Clinic

    Rochester, Minnesota, 55905, United States

  • Memorial Sloan Kettering Cancer Center

    New York, New York, 10065, United States

  • Montefiore Medical Center - Albert Einstein College of Medicine

    The Bronx, New York, 10467, United States

  • NYU Langone Health (Tisch Hospital, Kimmel Pavilion)

    New York, New York, 10016, United States

  • New York Presbyterian Columbia University Irving Medical Center

    New York, New York, 10032, United States

  • Rush University Medical Center

    Chicago, Illinois, 60612, United States

  • University of Alabama at Birmingham

    Birmingham, Alabama, 35233, United States

  • University of Arkansas

    Little Rock, Arkansas, 72205, United States

  • University of Pittsburgh - Magee Women's Hospital

    Pittsburgh, Pennsylvania, 15213, United States

  • University of Texas - MD Anderson Cancer Center

    Houston, Texas, 77030, United States

  • University of Texas - Southwestern Medical Center

    Dallas, Texas, 75390, United States

  • University of Washington Medical Center

    Seattle, Washington, 98195, United States

  • Washington University at St. Louis Medical Center

    St Louis, Missouri, 63110, United States

Conditions

Explore the condition pages connected to this study.