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Can a simple eyeglass test sharpen vision in keratoconus?

NCT ID NCT04174209

Knowledge-focused Sponsor: University Hospital, Clermont-Ferrand Source: ClinicalTrials.gov ↗

What the study statuses mean

This study's is highlighted.

Recruitment status, easiest to join first

Recruiting now
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed This study
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Aug 07, 2026 · Last updated Aug 07, 2026

Summary

This study compares three different methods for prescribing eyeglasses in people with keratoconus, a condition that thins and bulges the cornea, causing blurry vision. The goal is to see if the best method depends on the shape of the cornea, as measured by corneal topography. Researchers will test the Jackson Cross Cylinder, Astigmatic Dial, and Stenopeic Slit techniques in 52 adults with keratoconus to find which provides the sharpest vision. The findings could help eye doctors tailor eyeglass prescriptions to each patient's unique corneal shape.

What this could mean

Our plain-language read of the trial. This is informational only, not medical advice or a prediction.

Active substance
Three subjective refraction techniques: Jackson Cross Cylinder, Astigmatic Dial, and Stenopeic Slit
What this could lead to
If successful, this could help eye doctors choose the best eyeglass prescription method for each person with keratoconus, improving their vision without surgery.
What could go wrong
This is a small study (52 participants) and results may not apply to all keratoconus patients. The best technique may vary widely between individuals, and the study only looks at short-term vision correction, not long-term outcomes.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Phase

Not a phased trial

Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.

Participants

52 people

The number who actually took part.

Started

Nov 2019

Finished

Mar 2020

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Ages

18 years and older

Sex

Anyone

Healthy volunteers

Not accepted

This study is not open to healthy volunteers. The entry requirements below say who it is open to.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: * adult persons * patients with keratoconus * patients with alteration of visual acuity * ability to give informed consent to participate in the study * affiliation to a social security scheme Exclusion Criteria: * Keratoconus grafted with cornea or with intracorneal rings. * Central corneal opacities. * Presence of other eye diseases affecting visual acuity. * Patients under guardianship, curatorship or justice protection. * Pregnant or breastfeeding women. * Refusal to participate in the study.

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Conditions

The condition(s) this trial relates to.

keratoconus

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Alteration of visual acuity Keratoconus

Contacts and locations

Locations

  • Chu Clermont Ferrand

    Clermont-Ferrand, 63003, France

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Other studies related to the condition(s) this trial covers.