New PAH drug shows promise in Mid-Stage trial
NCT ID NCT05975905
First seen Nov 01, 2025 · Last updated May 22, 2026 · Updated 24 times
Summary
This study tested an investigational drug called KER-012 in 113 adults with pulmonary arterial hypertension (PAH), a serious lung condition that makes it hard to breathe. Participants took KER-012 or a placebo alongside their usual PAH medications. The goal was to see if KER-012 improves blood flow in the lungs and exercise ability, while checking for side effects.
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Contacts and locations
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Locations
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Site PI TROPOS Study Site 104
Stanford, California, 94305, United States
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TROPOS Study Site 100
Kansas City, Kansas, 66160, United States
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TROPOS Study Site 101
Ann Arbor, Michigan, 481091, United States
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TROPOS Study Site 102
Houston, Texas, 77030, United States
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TROPOS Study Site 103
Boston, Massachusetts, 02111, United States
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TROPOS Study Site 105
Torrance, California, 90502, United States
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TROPOS Study Site 106
Charleston, South Carolina, 29425, United States
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TROPOS Study Site 107
Tucson, Arizona, 85719, United States
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TROPOS Study Site 108
Jacksonville, Florida, 32224, United States
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TROPOS Study Site 109
Boston, Massachusetts, 02115, United States
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TROPOS Study Site 110
Louisville, Kentucky, 40202, United States
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TROPOS Study Site 111
Scottsdale, Arizona, 85258, United States
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TROPOS Study Site 112
Dallas, Texas, 75390, United States
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TROPOS Study Site 113
Cincinnati, Ohio, 45221, United States
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TROPOS Study Site 114
Albuquerque, New Mexico, 87106, United States
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TROPOS Study Site 115
St Louis, Missouri, 63110, United States
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TROPOS Study Site 200
Blumenau, 89030, Brazil
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TROPOS Study Site 201
São Paulo, 05403, Brazil
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TROPOS Study Site 202
Porto Alegre, 90020, Brazil
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TROPOS Study Site 320
Le Kremlin-Bicêtre, 94270, France
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TROPOS Study Site 340
Hanover, 30625, Germany
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TROPOS Study Site 341
Giesen, 35392, Germany
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TROPOS Study Site 342
Leipzig, 04103, Germany
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TROPOS Study Site 343
Heidelberg, 69120, Germany
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TROPOS Study Site 344
Homburg, 66424, Germany
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TROPOS Study Site 345
Regensburg, 93053, Germany
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TROPOS Study Site 400
Lisbon, 1769-001, Portugal
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TROPOS Study Site 401
Porto, 4099-001, Portugal
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TROPOS Study Site 402
Coimbra, 3000-075, Portugal
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TROPOS Study Site 403
Almada, 2805-267, Portugal
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TROPOS Study Site 410
Madrid, 28041, Spain
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TROPOS Study Site 411
Santander, 39008, Spain
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TROPOS Study Site 412
Barcelona, 39008, Spain
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TROPOS Study Site 413
Barcelona, 8035, Spain
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TROPOS Study Site 440
London, W12 0HS, United Kingdom
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TROPOS Study Site 441
Glasgow, G81 4DY, United Kingdom
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TROPOS Study Site 442
London, SW3 6NP, United Kingdom
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TROPOS Study Site 701
Krakow, 31-202, Poland
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TROPOS Study Site 702
Otwock, 05-400, Poland
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TROPOS Study Site 703
Poznan, 60-355, Poland
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TROPOS Study Site 704
Gdansk, 80-214, Poland
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TROPOS Study Site 705
Lodz, 91-347, Poland
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TROPOS Study Site 706
Poznan, 61-848, Poland
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TROPOS Study Site 800
Darlinghurst, 2010, Australia
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TROPOS Study Site 801
Sydney, 2095, Australia
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TROPOS Study Site 803
New Lambton Heights, 2305, Australia
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TROPOS Study Site 804
Camperdown, 2050, Australia
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TROPOS Study Site 805
Melbourne, Victoria, 3004, Australia
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TROPOS Study Site 807
Auchenflower, 4066, Australia
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TROPOS Study Site 880
Seoul, 06351, South Korea
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TROPOS Study Site 881
Incheon, 21565, South Korea
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TROPOS Study Site 882
Seoul, 03722, South Korea
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TROPOS Study Site 883
Seoul, 03080, South Korea
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TROPOS Study Site 890
Taipei, 11217, Taiwan
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TROPOS Study Site 891
Kaohsiung City, 81362, Taiwan
Conditions
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