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New drug combo targets Hard-to-Treat cancers in early trial

NCT ID NCT06108050

First seen Jan 05, 2026 · Last updated May 22, 2026 · Updated 25 times

Summary

This early-stage study tests a new drug called JZP898, alone or with another drug (pembrolizumab), in adults with advanced solid tumors that have not responded to standard treatments. The main goals are to check safety, find the right dose, and see if the drug shrinks tumors. About 177 participants will take part.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • California Cancer Associates for Research and Excellence

    RECRUITING

    Encinitas, California, 92024, United States

  • California Cancer Associates for Research and Excellence

    RECRUITING

    Fresno, California, 93270, United States

  • Duke University Medical Center - Duke Cancer Institute

    RECRUITING

    Durham, North Carolina, 27710, United States

  • Florida Cancer Specialists

    RECRUITING

    Orlando, Florida, 32827, United States

  • SCRI Oncology Partners

    RECRUITING

    Nashville, Tennessee, 37203, United States

  • Sarah Cannon Research Institute at HealthONE

    RECRUITING

    Denver, Colorado, 80218, United States

  • Sidney Kimmel Cancer Center at Thomas Jefferson University Hospital

    RECRUITING

    Philadelphia, Pennsylvania, 19107, United States

  • Texas Oncology - Baylor Charles A Sammons Cancer Center

    RECRUITING

    Dallas, Texas, 75246, United States

  • The University of Texas MD Anderson Cancer Center

    RECRUITING

    Houston, Texas, 77030, United States

  • Virginia Cancer Specialists

    RECRUITING

    Fairfax, Virginia, 22031, United States

Conditions

Explore the condition pages connected to this study.