New shot shows promise for tough psoriasis cases

NCT ID NCT05975268

Completed Disease control Sponsor: Shanghai Junshi Bioscience Co., Ltd. Source: ClinicalTrials.gov ↗

First seen Jan 04, 2026 · Last updated May 24, 2026 · Updated 22 times

Summary

This study tested a new medicine called JS005, given as a shot under the skin, for adults with moderate to severe plaque psoriasis. The trial involved 747 people and compared JS005 to a placebo to see if it could clear skin symptoms. The main goals were to measure how many patients had at least 90% improvement in their psoriasis (PASI 90) and clear or almost clear skin (sPGA 0/1) after 12 weeks. This is a disease-control treatment, not a cure, as ongoing management is expected.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

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Locations

Affiliated Hospital of Jiangsu University

Zhenjiang, Jiangsu, 212000, China
Baotou Central Hospital

Baotou, Neimenggu, 014040, China
Beijing Friendship Hospital, Capital Medical University

Beijing, Beijing Municipality, 100044, China
Beijing LuHe Hospital Capital Medical University

Beijing, Beijing Municipality, 101199, China
Beijing Tongren Hospital Affiliated to Capital Medical University

Beijing, Beijing Municipality, 100044, China
Beijing Tsinghua Changgung Hospital

Beijing, Beijing Municipality, 102218, China
Bethune First Hospital of Jilin University

Changchun, Jilin, 130021, China
Chengdu Second People's Hospital

Chengdu, Sichuan, 610017, China
China-Japan Friendship Hospital

Beijing, Beijing Municipality, 100044, China
Dermatology Hospital of Southern Medical University

Guangzhou, Guangdong, 510091, China
Dongguan People's Hospital

Dongguan, Guangdong, 523018, China
Guangdong General Hospital

Guangzhou, Guangdong, 510080, China
Guangzhou First People's Hospital

Guangzhou, Guangdong, 510180, China
Hangzhou First People's Hospital

Hangzhou, Zhejiang, 310006, China
Hangzhou Third People's Hospital

Hangzhou, Zhejiang, 310002, China
Inner Mongolia Baotou Steel Hospital

Baotou, Neimengu, 010000, China
Jiangxi Dermatology Hospital

Nanchang, Jiangxi, 330000, China
Jinan Central Hospital

Jinan, Shandong, 250013, China
Jingzhou Central Hospital

Jingzhou, Hubei, 434020, China
Lanzhou University Second Hospital

Lanzhou, Gansu, 730030, China
Lianyungang First People's Hospital

Lianyungang, Jiangsu, 222002, China
Medicine School of Xi'an Jiaotong University

Xian, Shanxi, 710004, China
Nanyang city first People's Hospital

Nanyang, Henan, 473000, China
Ningbo Huamei Hospital, University of Chinese Academy of Sciences

Beijing, Beijing Municipality, 100864, China
Ningxia Medical University General Hospital

Yinchuan, Ningxia, 750004, China
North East Central International Hospital Limited

Shenyang, Liaoning, China
Panjin Liao oil precious stone flower hospital

Panjin, Liaoning, 124011, China
Peking University People's Hospital

Beijing, Beijing Municipality, 100044, China
Peking University Third Hospital

Beijing, Beijing Municipality, 100044, China
Run Run Shaw Hospital, Zhejiang University School of Medicine

Hangzhou, Zhejiang, 310016, China
Shandong Dermatology Hospital

Jinan, Shandong, 250000, China
Shanghai Dermatology Hospital

Shanghai, Shanghai Municipality, 200050, China
Shengjing Hospital affiliated to China Medical University

Shenyang, Liaoning, 110004, China
Shenyang Hospital of Integrated Chinese and Western Medicine

Shenyang, Liaoning, 110021, China
Shenzhen People's Hospital

Shenzhen, Guangdong, 518020, China
Shiyan City People's Hospital

Shiyan, Hubei, 442000, China
Suining Central Hospital

Suining, Sichuan, 629000, China
Sun Yat-sen Memorial Hospital, Sun Yat-sen University

Guangzhou, Guangdong, 518107, China
The Affiliated Hospital of Chengde Medical College

Chengde, Hebei, China
The First Affiliated Hospital of Bengbu Medical College

Bengbu, Anhui, 233004, China
The First Affiliated Hospital of Chongqing Medical University

Chongqing, Chongqing Municipality, 400016, China
The First Affiliated Hospital of Fujian Medical University

Fuzhou, Fujian, 350005, China
The First Affiliated Hospital of Gannan Medical College

Ganzhou, Jiangxi, 341000, China
The First Affiliated Hospital of Soochow University

Suzhou, Jiangsu, 215123, China
The First Affiliated Hospital of Wenzhou Medical University

Wenzhou, Zhejiang, 325000, China
The First Affiliated Hospital of Xi 'an Jiaotong University City:Xian

Xi’an, Shanxi, 710061, China
The First Affiliated Hospital of Xinxiang Medical College

Xinxiang, Henan, 453100, China
The First Hospital of Hebei Medical University

Shijiazhuang, Hebei, 050000, China
The First Hospital of Jiaxing

Jiaxing, Zhejiang, 314001, China
The Second Affiliated Hospital of Anhui Medical University

Hefei, Anhui, 230601, China
The Second Affiliated Hospital of Kunming Medical University

Kunming, Yunnan, 650118, China
The Second Affiliated Hospital of Nanchang University

Nanchang, Jiangxi, 330006, China
The Second Affiliated Hospital of Xiamen Medical College

Xiamen, Fujian, 361023, China
The Second Hospital of Shanxi Medical University City:Taiyuan

Taiyuan, Shanxi, 030001, China
The Second Xiangya Hospital, Central South University

Changsha, Hunan, 410008, China
Tianjin Academy of Traditional Chinese Medicine Affiliated Hospital

Tianjin, Tianjin Municipality, 300120, China
West China Hospital of Sichuan University

Chengdu, Sichuan, 610041, China
Wuhan University People's Hospital

Wuhan, Hubei, 430060, China
Wuxi Second People's Hospital

Wuxi, Jiangsu, 214002, China
Xiangya Third Hospital, Central South University

Changsha, Hunan, 410013, China
Xingtai People's Hospital

Xingtai, Hebei, 054031, China
Yancheng First People's Hospital

Yancheng, Jiangsu, 224006, China
Zhejiang Provincial People's Hospital

Hangzhou, Zhejiang, 310014, China

Conditions

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MODERATE TO SEVERE CHRONIC PLAQUE PSORIASIS