New shot clears psoriasis in weeks: phase 3 trial shows promise

NCT ID NCT05975268

First seen Jan 04, 2026 · Last updated May 08, 2026 · Updated 20 times

Summary

This study tested a new medicine called JS005, given as a shot under the skin, for adults with moderate to severe plaque psoriasis. About 700 people took part. The goal was to see if JS005 could clear skin patches better than a placebo after 12 weeks. Results showed that more people on JS005 had at least 90% clearer skin and a score of 0 or 1 on the doctor's assessment. This is a disease-control treatment, not a cure, and may require ongoing use.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Locations

  • Affiliated Hospital of Jiangsu University

    Zhenjiang, Jiangsu, 212000, China

  • Baotou Central Hospital

    Baotou, Neimenggu, 014040, China

  • Beijing Friendship Hospital, Capital Medical University

    Beijing, Beijing Municipality, 100044, China

  • Beijing LuHe Hospital Capital Medical University

    Beijing, Beijing Municipality, 101199, China

  • Beijing Tongren Hospital Affiliated to Capital Medical University

    Beijing, Beijing Municipality, 100044, China

  • Beijing Tsinghua Changgung Hospital

    Beijing, Beijing Municipality, 102218, China

  • Bethune First Hospital of Jilin University

    Changchun, Jilin, 130021, China

  • Chengdu Second People's Hospital

    Chengdu, Sichuan, 610017, China

  • China-Japan Friendship Hospital

    Beijing, Beijing Municipality, 100044, China

  • Dermatology Hospital of Southern Medical University

    Guangzhou, Guangdong, 510091, China

  • Dongguan People's Hospital

    Dongguan, Guangdong, 523018, China

  • Guangdong General Hospital

    Guangzhou, Guangdong, 510080, China

  • Guangzhou First People's Hospital

    Guangzhou, Guangdong, 510180, China

  • Hangzhou First People's Hospital

    Hangzhou, Zhejiang, 310006, China

  • Hangzhou Third People's Hospital

    Hangzhou, Zhejiang, 310002, China

  • Inner Mongolia Baotou Steel Hospital

    Baotou, Neimengu, 010000, China

  • Jiangxi Dermatology Hospital

    Nanchang, Jiangxi, 330000, China

  • Jinan Central Hospital

    Jinan, Shandong, 250013, China

  • Jingzhou Central Hospital

    Jingzhou, Hubei, 434020, China

  • Lanzhou University Second Hospital

    Lanzhou, Gansu, 730030, China

  • Lianyungang First People's Hospital

    Lianyungang, Jiangsu, 222002, China

  • Medicine School of Xi'an Jiaotong University

    Xian, Shanxi, 710004, China

  • Nanyang city first People's Hospital

    Nanyang, Henan, 473000, China

  • Ningbo Huamei Hospital, University of Chinese Academy of Sciences

    Beijing, Beijing Municipality, 100864, China

  • Ningxia Medical University General Hospital

    Yinchuan, Ningxia, 750004, China

  • North East Central International Hospital Limited

    Shenyang, Liaoning, China

  • Panjin Liao oil precious stone flower hospital

    Panjin, Liaoning, 124011, China

  • Peking University People's Hospital

    Beijing, Beijing Municipality, 100044, China

  • Peking University Third Hospital

    Beijing, Beijing Municipality, 100044, China

  • Run Run Shaw Hospital, Zhejiang University School of Medicine

    Hangzhou, Zhejiang, 310016, China

  • Shandong Dermatology Hospital

    Jinan, Shandong, 250000, China

  • Shanghai Dermatology Hospital

    Shanghai, Shanghai Municipality, 200050, China

  • Shengjing Hospital affiliated to China Medical University

    Shenyang, Liaoning, 110004, China

  • Shenyang Hospital of Integrated Chinese and Western Medicine

    Shenyang, Liaoning, 110021, China

  • Shenzhen People's Hospital

    Shenzhen, Guangdong, 518020, China

  • Shiyan City People's Hospital

    Shiyan, Hubei, 442000, China

  • Suining Central Hospital

    Suining, Sichuan, 629000, China

  • Sun Yat-sen Memorial Hospital, Sun Yat-sen University

    Guangzhou, Guangdong, 518107, China

  • The Affiliated Hospital of Chengde Medical College

    Chengde, Hebei, China

  • The First Affiliated Hospital of Bengbu Medical College

    Bengbu, Anhui, 233004, China

  • The First Affiliated Hospital of Chongqing Medical University

    Chongqing, Chongqing Municipality, 400016, China

  • The First Affiliated Hospital of Fujian Medical University

    Fuzhou, Fujian, 350005, China

  • The First Affiliated Hospital of Gannan Medical College

    Ganzhou, Jiangxi, 341000, China

  • The First Affiliated Hospital of Soochow University

    Suzhou, Jiangsu, 215123, China

  • The First Affiliated Hospital of Wenzhou Medical University

    Wenzhou, Zhejiang, 325000, China

  • The First Affiliated Hospital of Xi 'an Jiaotong University City:Xian

    Xi’an, Shanxi, 710061, China

  • The First Affiliated Hospital of Xinxiang Medical College

    Xinxiang, Henan, 453100, China

  • The First Hospital of Hebei Medical University

    Shijiazhuang, Hebei, 050000, China

  • The First Hospital of Jiaxing

    Jiaxing, Zhejiang, 314001, China

  • The Second Affiliated Hospital of Anhui Medical University

    Hefei, Anhui, 230601, China

  • The Second Affiliated Hospital of Kunming Medical University

    Kunming, Yunnan, 650118, China

  • The Second Affiliated Hospital of Nanchang University

    Nanchang, Jiangxi, 330006, China

  • The Second Affiliated Hospital of Xiamen Medical College

    Xiamen, Fujian, 361023, China

  • The Second Hospital of Shanxi Medical University City:Taiyuan

    Taiyuan, Shanxi, 030001, China

  • The Second Xiangya Hospital, Central South University

    Changsha, Hunan, 410008, China

  • Tianjin Academy of Traditional Chinese Medicine Affiliated Hospital

    Tianjin, Tianjin Municipality, 300120, China

  • West China Hospital of Sichuan University

    Chengdu, Sichuan, 610041, China

  • Wuhan University People's Hospital

    Wuhan, Hubei, 430060, China

  • Wuxi Second People's Hospital

    Wuxi, Jiangsu, 214002, China

  • Xiangya Third Hospital, Central South University

    Changsha, Hunan, 410013, China

  • Xingtai People's Hospital

    Xingtai, Hebei, 054031, China

  • Yancheng First People's Hospital

    Yancheng, Jiangsu, 224006, China

  • Zhejiang Provincial People's Hospital

    Hangzhou, Zhejiang, 310014, China

Conditions

Explore the condition pages connected to this study.