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Ventilator patients at risk of joint stiffness: new study investigates

NCT ID NCT07339397

What the study statuses mean

This study's is highlighted.

Recruitment status, easiest to join first

Recruiting now
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed This study
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jun 24, 2026 · Last updated Sep 11, 2026 · Updated 3 times

Summary

This study follows 150 adult patients on ventilators in the ICU to see how often they develop joint contractures (stiff joints). Researchers measure joint movement regularly and track factors like sedation and immobility. The goal is to find what causes these contractures and help improve future care. No new treatments are being tested.

What this could mean

Our plain-language read of the trial. This is informational only, not medical advice or a prediction.

What this could lead to
If successful, this study could identify risk factors for joint stiffness in ICU patients, leading to better prevention and rehabilitation strategies.
What could go wrong
This is an observational study, not a treatment trial. It only gathers data and does not test any intervention, so it cannot directly improve patient outcomes.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Participants

150 people

The number who actually took part.

Started

Dec 2025

Finished

May 2026

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Who is studied

The study population consists of adult patients admitted to a tertiary-level intensive care unit who are mechanically ventilated, immobilized, and have impaired consciousness. Eligible participants are patients aged 18 years or older who are expected to remain in the ICU for at least seven days and are unable to mobilize independently due to their clinical condition. Patients with pre-existing joint contractures, neuromuscular diseases, spasticity, amputations, or conditions that preclude safe assessment of joint range of motion are excluded. All participants receive routine ICU care and standard physiotherapy according to institutional protocols, and no additional interventions are introduced for research purposes.

Ages

18 years and older

Sex

Anyone

Healthy volunteers

Not accepted

This study is not open to healthy volunteers. The entry requirements below say who it is open to.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: * • Adult patients aged 18 and over * Patients on mechanical ventilation and monitored in the intensive care unit for at least 7 days * Glasgow Coma Score ≤10 * Patients monitored immobile in the intensive care unit * Situations where informed consent can be obtained from the patient's legal representative Exclusion Criteria: * • Presence of pre-existing joint contracture, ankylosis, or amputation * Patients with severe burns, fractures, or surgical reasons preventing joint movement * Patients with a history of neuromuscular disease or spasticity * Patients who were immobilized for ≥1 week prior to admission to the intensive care unit * Hemodynamic instability situations where measurement is unreliable

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Conditions

The condition(s) this trial relates to.

Critical Illness

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • Fethi Sekin City Hospital

    Elâzığ, Elaziğ, 23050, Turkey (Türkiye)

More trials for these conditions

Other studies related to the condition(s) this trial covers.