Ventilator patients at risk of joint stiffness: new study investigates
NCT ID NCT07339397
First seen Jun 24, 2026 · Last updated Sep 11, 2026 · Updated 3 times
Summary
This study follows 150 adult patients on ventilators in the ICU to see how often they develop joint contractures (stiff joints). Researchers measure joint movement regularly and track factors like sedation and immobility. The goal is to find what causes these contractures and help improve future care. No new treatments are being tested.
What this could mean
Our plain-language read of the trial. This is informational only, not medical advice or a prediction.
- What this could lead to
- If successful, this study could identify risk factors for joint stiffness in ICU patients, leading to better prevention and rehabilitation strategies.
- What could go wrong
- This is an observational study, not a treatment trial. It only gathers data and does not test any intervention, so it cannot directly improve patient outcomes.
This is an AI summary of the original study and may miss details. Read our disclaimer.
Study facts
What this study's own registry entry says, in plain language.
- Participants
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150 people
The number who actually took part.
- Started
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Dec 2025
- Finished
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May 2026
- Lead sponsor
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Other sponsor
The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.
Who can take part
This study's own entry requirements. Only the study team can say for certain whether you qualify.
Who is studied
The study population consists of adult patients admitted to a tertiary-level intensive care unit who are mechanically ventilated, immobilized, and have impaired consciousness. Eligible participants are patients aged 18 years or older who are expected to remain in the ICU for at least seven days and are unable to mobilize independently due to their clinical condition. Patients with pre-existing joint contractures, neuromuscular diseases, spasticity, amputations, or conditions that preclude safe assessment of joint range of motion are excluded. All participants receive routine ICU care and standard physiotherapy according to institutional protocols, and no additional interventions are introduced for research purposes.
- Ages
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18 years and older
- Sex
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Anyone
- Healthy volunteers
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Not accepted
This study is not open to healthy volunteers. The entry requirements below say who it is open to.
Show the full entry requirements Hide the full entry requirements
Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.
Inclusion Criteria: * • Adult patients aged 18 and over * Patients on mechanical ventilation and monitored in the intensive care unit for at least 7 days * Glasgow Coma Score ≤10 * Patients monitored immobile in the intensive care unit * Situations where informed consent can be obtained from the patient's legal representative Exclusion Criteria: * • Presence of pre-existing joint contracture, ankylosis, or amputation * Patients with severe burns, fractures, or surgical reasons preventing joint movement * Patients with a history of neuromuscular disease or spasticity * Patients who were immobilized for ≥1 week prior to admission to the intensive care unit * Hemodynamic instability situations where measurement is unreliable
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
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Fethi Sekin City Hospital
Elâzığ, Elaziğ, 23050, Turkey (Türkiye)
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