Promising tremor device study pulled before it began
NCT ID NCT06346873
First seen Jun 27, 2026 · Last updated Jun 27, 2026
Summary
This study was designed to see if a biofeedback device called JOGO could help people with functional tremor, a condition where the body shakes uncontrollably. JOGO uses stickers on the skin to read muscle activity and then guides users through training sessions to reduce shaking. The study was withdrawn before any participants enrolled, so no results are available.
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Study facts
What this study's own registry entry says, in plain language.
- Phase
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Not a phased trial
Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.
- Started
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Jan 2025
- Finished
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Jan 2025
- Lead sponsor
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Other sponsor
The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.
Who can take part
This study's own entry requirements. Only the study team can say for certain whether you qualify.
- Ages
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18 years and older
- Sex
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Anyone
- Healthy volunteers
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Not accepted
This study is not open to healthy volunteers. The entry requirements below say who it is open to.
Show the full entry requirements Hide the full entry requirements
Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.
Inclusion Criteria: * Clinical diagnosis of functional tremor diagnosed by a Mayo Clinic Florida movement disorders specialist. * Must have access to reliable internet video. Exclusion Criteria: * Cognitive impairment (Montreal Cognitive Assessment greater than 26). * Currently taking any of the following medications to treat tremor: primidone, gabapentin, zonisamide, any non-selective beta blocker, any benzodiazepine. * Exposure to tremorgenic drugs or drug with withdrawal states within 30 days prior to the study start. * Direct or indirect trauma to the nervous system within 3 months preceding the onset of tremor. * Known history of other medical or neurological conditions that may cause or explain subject's tremor, including, but not limited to: Parkinson's disease, dystonia, cerebellar disease, traumatic brain injury, alcohol abuse or withdrawal, mercury poisoning, hyperthyroidism, pheochromocytoma, head trauma or cerebrovascular disease within 3 months prior to the onset of essential tremor, multiple sclerosis, polyneuropathy, family history of Fragile X syndrome. * Prior MR-guided focused ultrasound or surgical intervention (e.g., deep brain stimulation, ablative thalamotomy or gamma knife thalamotomy). * Botulinum toxin injection in the 6 months prior to screening. * Use of medication(s) in the past month that might produce tremor or interfere with the evaluation of tremor, such as, but not limited to: CNS-stimulants, lithium, amiodarone, metoclopramide, theophylline, and valproate. * Regular use of more than two units of alcohol per day. * Sporadic use of a benzodiazepine, sleep medication or anxiolytic to improve sleep performance. Stable use at a consistent dose is allowed if tremor persists against the background of regular medication use. * Current treatment with any investigational therapy for tremor.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
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Mayo Clinic in Florida
Jacksonville, Florida, 32224, United States
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Other studies related to the condition(s) this trial covers.
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