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New drug trial hopes to tame advanced cancers

NCT ID NCT07107230

First seen Nov 01, 2025 · Last updated May 24, 2026 · Updated 29 times

Summary

This early-stage study tests a new drug, JNJ-95437446, in people with advanced solid tumors like lung, colorectal, or head and neck cancers that have not responded to other treatments. The main goals are to find safe doses and check for side effects. About 380 participants will take part to see if the drug can shrink tumors and how long any benefit lasts.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • Florida Cancer Specialists

    RECRUITING

    Sarasota, Florida, 34232, United States

  • Hosp Univ Fund Jimenez Diaz

    RECRUITING

    Madrid, 28040, Spain

  • Hosp Univ Hm Sanchinarro

    RECRUITING

    Madrid, 28050, Spain

  • Hosp Univ Vall D Hebron

    RECRUITING

    Barcelona, 8035, Spain

  • Hosp. Univ. 12 de Octubre

    RECRUITING

    Madrid, 28041, Spain

  • NEXT Oncology

    RECRUITING

    Fairfax, Virginia, 22031, United States

  • Samsung Medical Center

    RECRUITING

    Seoul, 06351, South Korea

  • Severance Hospital Yonsei University Health System

    RECRUITING

    Seoul, 03722, South Korea

  • Tennessee Oncology

    RECRUITING

    Nashville, Tennessee, 37203, United States

Conditions

Explore the condition pages connected to this study.