Den här översättningen är inte klar ännu. Den här sidan är just nu på engelska.

Gå till den engelska sidan

Cure My Disease

Don't miss your cure!

 Log in / Sign up

New hope for hard-to-treat myeloma: experimental drug enters phase 2 trial

NCT ID NCT07266441

Disease control Sponsor: Janssen Research & Development, LLC Source: ClinicalTrials.gov ↗

What the study statuses mean

This study's is highlighted.

Recruitment status, easiest to join first

Recruiting now This study
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jun 27, 2026 · Last updated Aug 28, 2026 · Updated 4 times

Summary

This study tests an experimental drug called JNJ-79635322 in people with multiple myeloma that has returned or stopped responding after at least 3 prior treatments. The goal is to see how well the drug shrinks or controls the cancer. About 157 participants will receive the drug and be monitored for response and side effects.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Phase

Phase 2

Tests whether the treatment actually works, and watches for side effects, in a larger group.

Participants

About 157 people

The number the study aims to enrol. It can still change while the study runs.

Started

Feb 2026

Expected to finish

Dec 2028

An estimate. End dates often move.

Lead sponsor

A company

The lead sponsor is a pharmaceutical, biotech, or medical-device company.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Ages

18 years and older

Sex

Anyone

Healthy volunteers

Not accepted

This study is not open to healthy volunteers. The entry requirements below say who it is open to.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion: * Documented diagnosis of multiple myeloma (MM) as defined by the criteria below: 1. MM diagnosis according to the international myeloma working group (IMWG) diagnostic criteria 2. Measurable disease at screening as assessed by central laboratory * Received at least 3 prior lines of antimyeloma therapy including a proteasome inhibitor (PI), an immunomodulatory drug (IMiD), and an anti-cluster of differentiation (CD) 38 monoclonal antibody (mAb) * Documented evidence of progressive disease(PD) or failure to achieve a response to the last line of therapy based on investigator's determination of response by the IMWG criteria * Have discontinued concurrent use of any other anticancer treatment (including nonpalliative radiotherapy) or investigational agent * Have an eastern cooperative oncology group (ECOG) performance status (PS) of 0 to 2 at screening and immediately before the start of study treatment administration Exclusion: * Suspected or known allergies, hypersensitivity, or intolerance to excipients of JNJ-79635322 * Had major surgery within 2 weeks before first dose or has planned major surgery during study treatment phase * Known active or prior central nervous system (CNS) involvement or exhibits clinical signs of meningeal involvement of MM * Participant has leptomeningeal disease * Participant has a prior or concurrent second malignancy the natural history or treatment of which could likely interfere with any study endpoints of safety or the efficacy of the study treatment

Get updates

Get notified about this study

Sign up to get updates when this study changes or when new studies for Multiple myeloma are added.

Vår säkerhetsrekommendation!

Genom att skicka in godkänner du våra Användarvillkor

Conditions

The condition(s) this trial relates to.

plasma cell myeloma refractory plasma cell neoplasm

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Multiple myeloma

How to take part

Only the study team decides who joins. These are the ways to reach them.

  1. The places running it

    49 sites in 8 countries. The list below names each one and where it is.

  2. The official record

    ClinicalTrials.gov lists the study team's own contact details, including names and phone numbers. We don't republish those.

    Open the record ↗

  3. A doctor treating you

    A doctor who knows your case can contact a study site on your behalf, and can tell you whether this study is worth pursuing at all.

Contacts and locations

Locations

  • AOU Policlinico Umberto I

    RECRUITING

    Roma, 00161, Italy

  • ASST Papa Giovanni XXIII Bergamo

    RECRUITING

    Bergamo, 24127, Italy

  • Ankara University Medical Faculty

    RECRUITING

    Ankara, 06590, Turkey (Türkiye)

  • Asan Medical Center

    RECRUITING

    Seoul, 05505, South Korea

  • Azienda Ospedaliera S Croce e Carle Cuneo

    RECRUITING

    Cuneo, 12100, Italy

  • Azienda Ospedaliero Universitaria Careggi

    RECRUITING

    Florence, 50134, Italy

  • Azienda Ospedaliero Universitaria Policlinico Paolo Giaccone

    RECRUITING

    Palermo, 90127, Italy

  • Banner MD Anderson Cancer Center

    ACTIVE_NOT_RECRUITING

    Gilbert, Arizona, 85234, United States

  • Beijing Chaoyang Hospital

    RECRUITING

    Chaoyang District, 100020, China

  • Cancer Care Specialists of Central Illinois

    RECRUITING

    O'Fallon, Illinois, 62269, United States

  • Cancer Specialists of North Florida

    ACTIVE_NOT_RECRUITING

    Jacksonville, Florida, 32256, United States

  • Cancer and Blood Specialty Clinic

    ACTIVE_NOT_RECRUITING

    Los Alamitos, California, 90720, United States

  • Centro Ricerche Cliniche di Verona S r l

    RECRUITING

    Verona, 37134, Italy

  • Chonnam National University Hwasun Hospital

    RECRUITING

    Jeollanam-do, 58128, South Korea

  • City of Hope

    ACTIVE_NOT_RECRUITING

    Duarte, California, 91010, United States

  • City of Hope Orange County Lennar Foundation Cancer Center

    ACTIVE_NOT_RECRUITING

    Irvine, California, 92618, United States

  • Cleveland Clinic Foundtation

    ACTIVE_NOT_RECRUITING

    Cleveland, Ohio, 44195, United States

  • Colorado Blood Cancer Institute

    ACTIVE_NOT_RECRUITING

    Denver, Colorado, 80218, United States

  • Emory University

    ACTIVE_NOT_RECRUITING

    Atlanta, Georgia, 30322, United States

  • Ha'Emek Medical Center

    RECRUITING

    Afula, 1834111, Israel

  • Hadassah Medical Center

    RECRUITING

    Jerusalem, 9112000, Israel

  • Hillel Yaffe Medical Center

    RECRUITING

    Hadera, 3820302, Israel

  • IRCCS Policlinico San Matteo, Università degli studi di Pavi

    RECRUITING

    Pavia, 27100, Italy

  • Istanbul Florance Nightingale Hospital

    RECRUITING

    Istanbul, 34381, Turkey (Türkiye)

  • Levine Cancer Institute

    ACTIVE_NOT_RECRUITING

    Charlotte, North Carolina, 28204, United States

  • Liv Hospital Ankara

    RECRUITING

    Ankara, 06680, Turkey (Türkiye)

  • MD Anderson Cancer Center

    ACTIVE_NOT_RECRUITING

    Houston, Texas, 77030, United States

  • Massachusetts General Hospital

    ACTIVE_NOT_RECRUITING

    Boston, Massachusetts, 02114, United States

  • Medipol University Hospital

    RECRUITING

    Istanbul, 34214, Turkey (Türkiye)

  • Memorial Antalya Hospital

    RECRUITING

    Antalya, 07025, Turkey (Türkiye)

  • Memorial Sloan Kettering Cancer Center

    ACTIVE_NOT_RECRUITING

    New York, New York, 10065, United States

  • Mission Cancer Blood

    RECRUITING

    Waukee, Iowa, 50263, United States

  • National Hospital Organization Okayama Medical Center

    RECRUITING

    Okayama, 701-1192, Japan

  • National Hospital Organization Shibukawa Medical Center

    RECRUITING

    Gunma, 377-0280, Japan

  • NorthWest Medical Specialties, PLLC

    ACTIVE_NOT_RECRUITING

    Tacoma, Washington, 98405, United States

  • Northside Hospital Cancer Institute

    RECRUITING

    Atlanta, Georgia, 30342, United States

  • O Neal Comprehensive Cancer Center at UAB

    ACTIVE_NOT_RECRUITING

    Birmingham, Alabama, 35294, United States

  • Oncology Associates of Oregon PC Willamette Valley Cancer Institute

    RECRUITING

    Eugene, Oregon, 97401, United States

  • Oncology Consultants Texas

    ACTIVE_NOT_RECRUITING

    Houston, Texas, 77030, United States

  • Peking Union Medical College Hospital

    RECRUITING

    Beijing, 100006, China

  • Policlinico Sant'Orsola Malpighi

    RECRUITING

    Bologna, 40138, Italy

  • Presidio Ospedaliero Pescara

    RECRUITING

    Pescara, 65124, Italy

  • Rabin Medical Center

    RECRUITING

    Petah Tikva, 4941492, Israel

  • Rocky Mountain Cancer Centers

    RECRUITING

    Aurora, Colorado, 80012, United States

  • Rutgers Cancer Institute

    ACTIVE_NOT_RECRUITING

    New Brunswick, New Jersey, 08901, United States

  • SCRI Oncology Partners

    ACTIVE_NOT_RECRUITING

    Nashville, Tennessee, 37203, United States

  • Sakarya Üniversitesi Tıp Fakültesi Hastanesi

    RECRUITING

    Sakarya, 54050, Turkey (Türkiye)

  • Samodzielny Publiczny Zaklad Opieki Zdrowotnej Szpital Uniwersytecki w Krakowie

    RECRUITING

    Krakow, 30 688, Poland

  • Samson Assuta Ashdod University Hospital

    RECRUITING

    Ashdod, 7747629, Israel

  • Samsung Medical Center

    RECRUITING

    Seoul, 06351, South Korea

  • Seoul National University Hospital

    RECRUITING

    Seoul, 03080, South Korea

  • Severance Hospital Yonsei University Health System

    RECRUITING

    Seoul, 03722, South Korea

  • Shanghai Fourth People s Hospital

    RECRUITING

    Shanghai, 200434, China

  • Sun Yat Sen University Cancer Center

    RECRUITING

    Guangzhou, 510700, China

  • Swietokrzyskie Centrum Onkologii SPZOZ w Kielcach

    RECRUITING

    Kielce, 25 734, Poland

  • Szpital Specjalistyczny w Brzozowie Podkarpacki Osrodek Onkologiczny im Ks B Markiewicza

    RECRUITING

    Brzozów, 36 200, Poland

  • Tel Aviv Sourasky Medical Center

    RECRUITING

    Tel Aviv, 6423906, Israel

  • Tennessee Oncology, PLLC

    RECRUITING

    Nashville, Tennessee, 37203, United States

  • Texas Oncology

    ACTIVE_NOT_RECRUITING

    Austin, Texas, 78705, United States

  • Texas Oncology - Northeast

    ACTIVE_NOT_RECRUITING

    Tyler, Texas, 75702, United States

  • The Catholic University of Korea Seoul St Marys Hospital

    RECRUITING

    Seoul, 06591, South Korea

  • University of California San Francisco

    ACTIVE_NOT_RECRUITING

    San Francisco, California, 94143, United States

  • University of Iowa

    ACTIVE_NOT_RECRUITING

    Iowa City, Iowa, 52242, United States

  • University of Pennsylvania

    ACTIVE_NOT_RECRUITING

    Philadelphia, Pennsylvania, 19104, United States

  • Uniwersytecki Szpital Kliniczny Nr 1 w Lublinie

    RECRUITING

    Lublin, 20 081, Poland

  • Uniwersytecki Szpital Kliniczny im Jana Mikulicza Radeckiego we Wroclawiu

    RECRUITING

    Wroclaw, 50 367, Poland

  • Uniwersytecki Szpital Kliniczny w Poznaniu

    RECRUITING

    Poznan, 60-569, Poland

  • Virginia Cancer Specialists

    RECRUITING

    Fairfax, Virginia, 22031, United States

  • Virginia Oncology Associates

    RECRUITING

    Norfolk, Virginia, 23502, United States

  • Wojewodzki Szpital Zespolony im L Rydygiera w Toruniu

    RECRUITING

    Torun, 87 100, Poland

  • Wojewodzkie Wielospecjalistyczne Centrum Onkologii i Traumatologii im M Kopernika w Lodzi

    RECRUITING

    Lodz, 93 513, Poland

More trials for these conditions

Other studies related to the condition(s) this trial covers.