New immune therapy targets Hard-to-Treat prostate cancer
NCT ID NCT04898634
First seen Sep 30, 2025 · Last updated May 21, 2026 · Updated 27 times
Summary
This early-stage study tests a new drug called JNJ-78278343 for men with advanced prostate cancer that has spread. The drug works by redirecting the body's immune T-cells to attack cancer cells that carry a protein called KLK2. The main goals are to find the safest and most effective dose and to check for side effects. About 216 men who have already tried other treatments will take part.
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This is a summary of
the original study
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Contacts and locations
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Locations
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APHM Hopital Timone
Marseille, 13005, France
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Antoni van Leeuwenhoek
Amsterdam, 1066 CX, Netherlands
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Centre Leon Berard
Lyon, 69373, France
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Chongqing University Cancer Hospital
Chongqing, 400030, China
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Columbia University Medical Center Herbert Irving Pavilion
New York, New York, 10032, United States
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Erasmus MC
Rotterdam, 3015 GD, Netherlands
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First Affiliated Hospital Of Wenzhou Medical College
Wenzhou, 325399, China
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Hosp Univ Fund Jimenez Diaz
Madrid, 28040, Spain
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Hosp Univ Hm Sanchinarro
Madrid, 28050, Spain
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Hosp Virgen de La Victoria
Málaga, 29010, Spain
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Institut Gustave Roussy
Villejuif, 94800, France
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Memorial Sloan Kettering Cancer Center
New York, New York, 10065, United States
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National Cancer Center Hospital East
Kashiwa, 277 8577, Japan
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Peking University Third Hospital
Beijing, 100191, China
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Sun Yat Sen University Cancer Center
Guangzhou, 510710, China
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University of Washington
Seattle, Washington, 98195-9472, United States
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Yokohama City University Medical Center
Yokohama, 232 0024, Japan
Conditions
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