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Weekly shot aims to stop Kids' arthritis from spreading

NCT ID NCT03841357

Summary

This study tested whether weekly injections of a medication called abatacept could prevent mild juvenile arthritis from becoming more severe. Children with recent-onset arthritis affecting four or fewer joints received either the injections plus standard care or standard care alone for 24 weeks, then were followed for up to 18 months. The goal was to see if the treatment could prevent the arthritis from spreading to more joints, prevent eye inflammation, or reduce the need for stronger medications.

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Contacts and locations

Locations

  • Boston Children's Hospital

    Boston, Massachusetts, 02115, United States

  • Children's Hospital at Montefiore/ Albert Einstein University Hospital

    The Bronx, New York, 10461, United States

  • Children's Hospital of Philadelphia

    Philadelphia, Pennsylvania, 19104, United States

  • Cincinnati Children's Hospital Medical Center

    Cincinnati, Ohio, 45229, United States

  • Hackensack University Medical Center

    Hackensack, New Jersey, 07601, United States

  • Mayo Clinic

    Rochester, Minnesota, 55905, United States

  • MetroHealth System

    Cleveland, Ohio, 44109, United States

  • Monroe Carell Jr Children's Hospital at Vanderbilt

    Nashville, Tennessee, 37232, United States

  • Nationwide Children's Hospital

    Columbus, Ohio, 43205, United States

  • Riley Hospital for Children at Indiana University Health

    Indianapolis, Indiana, 46202, United States

  • Seattle Children's Hospital

    Seattle, Washington, 98105, United States

  • Shands at the University of Florida

    Gainesville, Florida, 32610, United States

  • The Children's Hospital Colorado

    Aurora, Colorado, 80045, United States

  • University of California at San Francisco Medical Center

    San Francisco, California, 94143, United States

  • University of Iowa Hospitals of Clinics

    Iowa City, Iowa, 52242, United States

  • University of Louisville School of Medicine/ Norton Charities Pediatric Clinical Research Unit

    Louisville, Kentucky, 40202, United States

  • University of Minnesota; Children's Hospital and Clinics of Minnesota

    Minneapolis, Minnesota, 55454, United States

  • University of North Carolina

    Chapel Hill, North Carolina, 27514, United States

  • University of Utah

    Salt Lake City, Utah, 84158, United States

Conditions

Explore the condition pages connected to this study.