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New drug for fatty liver disease takes first step in human testing

NCT ID NCT06308874

First seen Jan 03, 2026 · Last updated Jun 20, 2026 · Updated 26 times

Summary

This early-stage trial tested the safety and tolerability of a single dose of J2H-1702 in 16 healthy women. The drug is being developed for non-alcoholic steatohepatitis (NASH), a serious liver condition. Researchers measured how the body processes the drug and its effects, but this study does not yet test if it works against the disease.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Locations

  • J2H Biotech

    Suwon, Gyeonggi-do, 16684, South Korea

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

J2H-1702

What this could lead to

If successful, this could lead to further studies testing J2H-1702 as a potential treatment for non-alcoholic steatohepatitis (NASH), a liver disease.

What could go wrong

This is a very early Phase 1 trial with only 16 healthy women, not patients. It only tests safety and drug levels, not whether it works for NASH. Many drugs fail at this stage.

Conditions

The condition(s) this trial relates to.

metabolic dysfunction-associated steatotic liver disease

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.