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New pill shows promise for rare bile duct cancer in japanese patients

NCT ID NCT06081829

First seen Jan 11, 2026 · Last updated May 25, 2026 · Updated 13 times

Summary

This study tests an oral drug called ivosidenib in 12 Japanese patients with advanced bile duct cancer that has a specific IDH1 gene mutation. Participants take the pill daily in 28-day cycles until the cancer worsens or side effects become too severe. The goal is to see if the drug can delay cancer growth and improve survival.

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Contacts and locations

Locations

  • Hokkaido University Hospital (JPN-006)

    Sapporo, 060-8648, Japan

  • Kanagawa Cancer Center (JPN-003)

    Yokohama, 241-8515, Japan

  • Kumamoto University Hospital (JPN-004)

    Kumamoto, 860-8556, Japan

  • National Cancer Center Hospital (JPN-001)

    Tokyo, Japan

  • National Cancer Center Hospital East (JPN-002)

    Kashiwa, 277-8577, Japan

  • National Hospital Organization Shikoku Cancer Center (JPN-007)

    Matsuyama, 791-0280, Japan

  • Osaka International Cancer Institute (JPN-005)

    Osaka, 541-8567, Japan

Conditions

Explore the condition pages connected to this study.