New pill targets rare bile duct cancer gene in japanese patients

NCT ID NCT06081829

First seen Jan 11, 2026 · Last updated May 14, 2026 · Updated 11 times

Summary

This study tests a daily oral drug called ivosidenib in 12 Japanese adults with advanced bile duct cancer that has a specific IDH1 gene mutation and has already been treated with chemotherapy. The goal is to see if the drug can stop or slow the cancer from growing. Participants take the pill in 28-day cycles until the cancer worsens or side effects become too severe.

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Contacts and locations

Locations

  • Hokkaido University Hospital (JPN-006)

    Sapporo, 060-8648, Japan

  • Kanagawa Cancer Center (JPN-003)

    Yokohama, 241-8515, Japan

  • Kumamoto University Hospital (JPN-004)

    Kumamoto, 860-8556, Japan

  • National Cancer Center Hospital (JPN-001)

    Tokyo, Japan

  • National Cancer Center Hospital East (JPN-002)

    Kashiwa, 277-8577, Japan

  • National Hospital Organization Shikoku Cancer Center (JPN-007)

    Matsuyama, 791-0280, Japan

  • Osaka International Cancer Institute (JPN-005)

    Osaka, 541-8567, Japan

Conditions

Explore the condition pages connected to this study.