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New hope for bile duct cancer: targeted combo targets IDH1 mutation

NCT ID NCT07282262

First seen Dec 29, 2025 · Last updated May 19, 2026 · Updated 24 times

Summary

This study tests a precision medicine approach for people with advanced bile duct cancer that has a specific genetic change called an IDH1 mutation. Participants will receive a combination of ivosidenib (a targeted pill) plus either lenvatinib or an immunotherapy drug. The goal is to see if this treatment can shrink tumors or slow disease progression in patients whose cancer has not responded to standard chemotherapy.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • Beijing Peking Union Medical College Hospital Outpatient Department

    RECRUITING

    Beijing, China

    Contact Phone: •••-•••-•••• Email: •••••@•••••

Conditions

Explore the condition pages connected to this study.