New combo therapy targets rare bile duct cancer mutation in late-stage trial

NCT ID NCT07282262

First seen Dec 29, 2025 · Last updated May 16, 2026 · Updated 23 times

Summary

This study tests a drug called ivosidenib, combined with lenvatinib or an immunotherapy, for people with advanced bile duct cancer that has a specific IDH1 gene change and has stopped responding to standard chemotherapy. The goal is to see if this targeted approach can shrink tumors or slow the cancer's growth. About 300 participants will receive the treatment and be monitored for safety and effectiveness.

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Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • Beijing Peking Union Medical College Hospital Outpatient Department

    RECRUITING

    Beijing, China

    Contact Phone: •••-•••-•••• Email: •••••@•••••

Conditions

Explore the condition pages connected to this study.