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New hope for hard-to-treat nose and throat cancer: four experimental combos tested

NCT ID NCT07070479

First seen Oct 31, 2025 · Last updated May 22, 2026 · Updated 21 times

Summary

This study tests four different drug combinations in 208 adults with advanced nasopharyngeal cancer that has stopped responding to standard treatments, including PD-1 inhibitors. The goal is to see which combination best shrinks tumors and controls the disease. Participants will receive one of four regimens: ivonescimab alone, ivonescimab plus nimotuzumab, liposomal mitoxantrone plus an anti-PD-1 antibody, or liposomal irinotecan plus S-1.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • Cancer Center of Guangzhou Medical University

    NOT_YET_RECRUITING

    Guangzhou, Guangdong, China

    Contact Phone: •••-•••-••••

  • Guangdong Provincial People's Hospital

    NOT_YET_RECRUITING

    Guangzhou, Guangdong, China

    Contact Phone: •••-•••-••••

  • Sun Yat-sen University Cancer Center

    NOT_YET_RECRUITING

    Guangzhou, Guangdong, China

    Contact Phone: •••-•••-••••

  • The Fifth Affiliated Hospital of Sun Yat-sen University

    RECRUITING

    Zhuhai, Guangdong, China

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Xiangya Hospital, Central South University

    NOT_YET_RECRUITING

    Changsha, Hunan, China

    Contact Phone: •••-•••-••••

  • Zhongshan People's Hospital

    NOT_YET_RECRUITING

    Zhongshan, Guangdong, China

    Contact Phone: •••-•••-••••

Conditions

Explore the condition pages connected to this study.