Could a common numbing drug cut Post-Surgery opioid use?
NCT ID NCT07076641
First seen Jan 15, 2026 · Last updated Jun 23, 2026 · Updated 26 times
Summary
This study tests whether giving lidocaine through an IV, along with a spinal morphine injection, can lower the amount of morphine patients need after major digestive or abdominal surgery. About 76 adults having planned open abdominal surgery will be randomly assigned to receive either lidocaine or a placebo. The goal is to see if lidocaine helps control pain better and reduces morphine use in the first 48 hours after surgery.
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the original study
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Contacts and locations
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Study contacts
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Contact
Phone: •••-•••-•••• Email: •••••@•••••
Locations
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Hôpital Privé Jean Mermoz
Lyon, 69008, France
Contact Email: •••••@•••••
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
Active substance
lidocaine (intravenous)
What this could lead to
If it works, this could offer a way to reduce morphine use after major abdominal surgery, potentially lowering side effects like nausea or drowsiness.
What could go wrong
This is a small, early-stage trial with only 76 participants, so results may not apply to everyone. Lidocaine can cause side effects like dizziness or heart issues.
Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.