New drug could shrink nasal polyps and ease breathing
NCT ID NCT06834347
First seen Oct 31, 2025 · Last updated May 24, 2026 · Updated 32 times
Summary
This study tests a drug called itepekimab for adults with chronic sinusitis and nasal polyps that are not well controlled. About 231 participants will receive either the drug or a placebo for 52 weeks, along with standard nasal spray. The goal is to see if itepekimab can shrink polyps and reduce nasal congestion.
Disclaimer
Read more
Show less
This is a summary of
the original study
.
Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
Get updates
Get notified about this study
Sign up to get updates when this study changes or when new studies for CHRONIC RHINOSINUSITIS WITH NASAL POLYPS are added.
Genom att skicka in godkänner du våra Användarvillkor
Contacts and locations
Show contact details
Enter your email to view the contact information for this study.
Genom att skicka in godkänner du våra Användarvillkor
Locations
-
ASST Santi Paolo e Carlo-Presidio Ospedale San Paolo-Site Number : 3800006
Milan, Milano, 20142, Italy
-
Advanced Research Associates (ARA) Professionals- Site Number : 8400011
Miami, Florida, 33176, United States
-
Alamo ENT Associates- Site Number : 8400065
San Antonio, Texas, 78258, United States
-
Azienda Ospedale - Università Padova-Site Number : 3800008
Padua, Padova, 35128, Italy
-
Azienda Ospedaliera Universitaria Careggi-Site Number : 3800011
Florence, Firenze, 50134, Italy
-
Azienda Ospedaliero-Universitaria di Ferrara-Site Number: 3800004
Cona, Ferrara, 44124, Italy
-
Breathe Clear Institute of Sinus and Allergy Relief- Site Number : 8400040
Torrance, California, 90503, United States
-
Centro Internacional de Pesquisa Clínica (CIPES)- Site Number : 0760005
São José dos Campos, São Paulo, 12230-001, Brazil
-
Deaconess Clinic Allergy East- Site Number : 8400056
Evansville, Indiana, 47715, United States
-
ENT Associates of Texas - McKinne- Site Number : 8400062
McKinney, Texas, 75070, United States
-
Eastern Virginia Medical School (EVMS) Medical Group- Site Number : 8400046
Norfolk, Virginia, 23510, United States
-
Emory University School of Medicine- Grady Campus- Site Number : 8400047
Atlanta, Georgia, 30303, United States
-
Essential Medical Research- Site Number : 8400066
Tulsa, Oklahoma, 74137, United States
-
Fondazione Policlinico Universitario Agostino Gemelli IRCCS-Site Number: 3800002
Rome, Roma, 00168, Italy
-
Hospital Israelita Albert Einstein- Site Number : 0760001
São Paulo, 05651-901, Brazil
-
Hospital das Clinicas da Faculdade de Medicina de Ribeirao Preto- Site Number : 0760002
Ribeirão Preto, São Paulo, 14049-900, Brazil
-
Houston Methodist Hospital- Site Number : 8400054
Houston, Texas, 77030, United States
-
IRCCS Ospedale Policlinico San Martino-Site Number : 3800013
Genoa, Genova, 16132, Italy
-
Investigational Site Number : 0320001
Buenos Aires, 1425, Argentina
-
Investigational Site Number : 0320002
La Plata, Buenos Aires, 1900, Argentina
-
Investigational Site Number : 0320003
Mendoza, 5500, Argentina
-
Investigational Site Number : 0320004
Rosario, Santa Fe Province, 2000, Argentina
-
Investigational Site Number : 0320005
Buenos Aires, 1638, Argentina
-
Investigational Site Number : 0400001
Vienna, 1090, Austria
-
Investigational Site Number : 0400002
Linz, 4010, Austria
-
Investigational Site Number : 0400005
Graz, 8036, Austria
-
Investigational Site Number : 1240001
Québec, Quebec, G1V 4G5, Canada
-
Investigational Site Number : 1240002
Montreal, Quebec, H4a 3j1, Canada
-
Investigational Site Number : 1240005
London, Ontario, N6A 4V2, Canada
-
Investigational Site Number : 1520001
Santiago, Reg Metropolitana de Santiago, 8207257, Chile
-
Investigational Site Number : 1520002
Santiago, Reg Metropolitana de Santiago, 7500692, Chile
-
Investigational Site Number : 1520003
Talca, Maule Region, 3465584, Chile
-
Investigational Site Number : 1520004
Lo Barnechea, Reg Metropolitana de Santiago, 7691236, Chile
-
Investigational Site Number : 1520005
Viña del Mar, Valparaiso, 2540364, Chile
-
Investigational Site Number : 1520006
Valdivia, Los Ríos Region, 5110683, Chile
-
Investigational Site Number : 2460002
Kuopio, 70210, Finland
-
Investigational Site Number : 2460003
Helsinki, 00130, Finland
-
Investigational Site Number : 2460004
Helsinki, 00029, Finland
-
Investigational Site Number : 2760001
Tübingen, 72076, Germany
-
Investigational Site Number : 2760002
Münster, 48149, Germany
-
Investigational Site Number : 2760003
Würzburg, 97080, Germany
-
Investigational Site Number : 2760004
Berlin, 10117, Germany
-
Investigational Site Number : 2760005
Wiesbaden, 65205, Germany
-
Investigational Site Number : 2760007
Frankfurt, 60318, Germany
-
Investigational Site Number : 2760008
Hamburg, 22523, Germany
-
Investigational Site Number : 2760009
Landsberg, 06188, Germany
-
Investigational Site Number : 3480001
Pécs, 7621, Hungary
-
Investigational Site Number : 3480002
Budapest, 1046, Hungary
-
Investigational Site Number : 3480003
Nyíregyháza, 4400, Hungary
-
Investigational Site Number : 3480004
Debrecen, 4032, Hungary
-
Investigational Site Number : 3760004
Kefar Sava, 4428164, Israel
-
Investigational Site Number : 3760005
Petah Tikva, 4941492, Israel
-
Investigational Site Number : 3760007
Haifa, 3436212, Israel
-
Investigational Site Number : 3760009
Tel Aviv, 6423906, Israel
-
Investigational Site Number : 3920001
Fukuoka, 812-0053, Japan
-
Investigational Site Number : 3920002
Odawara, Kanagawa, 250-8558, Japan
-
Investigational Site Number : 3920003
Kumamoto, 860-0814, Japan
-
Investigational Site Number : 3920004
Narita, Chiba, 286-8520, Japan
-
Investigational Site Number : 3920005
Suwa, Nagano, 392-0027, Japan
-
Investigational Site Number : 3920006
Fukui, 910-1104, Japan
-
Investigational Site Number : 3920008
Tokyo, 153-8515, Japan
-
Investigational Site Number : 3920009
Isehara, Kanagawa, 259-1193, Japan
-
Investigational Site Number : 3920010
Ichikawa, Chiba, 272-0143, Japan
-
Investigational Site Number : 3920011
Hiroshima, 734-0004, Japan
-
Investigational Site Number : 3920012
Kusatsu, Shiga, 525-0066, Japan
-
Investigational Site Number : 3920013
Niigata, 951-8520, Japan
-
Investigational Site Number : 3920014
Yokohama, Kanagawa, 236-0037, Japan
-
Investigational Site Number : 4100001
Seoul, Seoul-teukbyeolsi, 07061, South Korea
-
Investigational Site Number : 4100002
Seoul, Seoul-teukbyeolsi, 06351, South Korea
-
Investigational Site Number : 4100003
Seoul, Seoul-teukbyeolsi, 03080, South Korea
-
Investigational Site Number : 4100004
Seoul, Seoul-teukbyeolsi, 03722, South Korea
-
Investigational Site Number : 4100005
Cheonan-Si, Chungcheongnam-do, 31116, South Korea
-
Investigational Site Number : 4100006
Seoul, 02841, South Korea
-
Investigational Site Number : 4100008
Incheon, Incheon-gwangyeoksi, 21565, South Korea
-
Investigational Site Number : 4100009
Seongnam-si, Gyeonggi-do, 13620, South Korea
-
Investigational Site Number : 4840003
Durango, 34000, Mexico
-
Investigational Site Number : 4840004
Chihuahua City, 31000, Mexico
-
Investigational Site Number : 5280002
Leiderdorp, 2353 GA, Netherlands
-
Investigational Site Number : 5280004
Alkmaar, 1815 JD, Netherlands
-
Investigational Site Number : 6160001
Wroclaw, Lower Silesian Voivodeship, 53-149, Poland
-
Investigational Site Number : 6160002
Warsaw, Masovian Voivodeship, 00-909, Poland
-
Investigational Site Number : 6160003
Bialystok, Podlaskie Voivodeship, 15-756, Poland
-
Investigational Site Number : 6160004
Wroclaw, Lower Silesian Voivodeship, 53-301, Poland
-
Investigational Site Number : 6160005
Lublin, Lublin Voivodeship, 20-363, Poland
-
Investigational Site Number : 6160006
Krakow, Lesser Poland Voivodeship, 31-513, Poland
-
Investigational Site Number : 6200001
Santa Maria da Feira, 4520-211, Portugal
-
Investigational Site Number : 6200002
Porto, 3814-501, Portugal
-
Investigational Site Number : 6200003
Guimarães, 4800-055, Portugal
-
Investigational Site Number : 6200004
Matosinhos Municipality, 4464-513, Portugal
-
Investigational Site Number : 7240001
Majadahonda, Madrid, 28222, Spain
-
Investigational Site Number : 7240002
Barcelona, Catalunya [Cataluña], 08036, Spain
-
Investigational Site Number : 7240003
Santiago de Compostela, A Coruña [La Coruña], 15706, Spain
-
Investigational Site Number : 7240004
Jerez de la Frontera, Cádiz, 11407, Spain
-
Investigational Site Number : 7240005
Zaragoza, 50009, Spain
-
Investigational Site Number : 7240006
Seville, Sevilla, 41009, Spain
-
Investigational Site Number : 7240007
Santiago de Compostela, A Coruña [La Coruña], 15702, Spain
-
Investigational Site Number : 7240008
Barcelona, Barcelona [Barcelona], 08022, Spain
-
Investigational Site Number : 7240009
Sabadell, 08208, Spain
-
Investigational Site Number : 7520001
Solna, 171 64, Sweden
-
Investigational Site Number : 7520002
Lund, 221 85, Sweden
-
Investigational Site Number : 7520004
Stockholm, 114 86, Sweden
-
Investigational Site Number : 7920001
Istanbul, 34093, Turkey (Türkiye)
-
Investigational Site Number : 7920002
Istanbul, 34865, Turkey (Türkiye)
-
Investigational Site Number : 7920003
Ankara, 06230, Turkey (Türkiye)
-
Investigational Site Number : 8260001
Newcastle upon Tyne, NE7 7DN, United Kingdom
-
Investigational Site Number : 8260002
London, London, City of, NW1 2BU, United Kingdom
-
Investigational Site Number : 8260004
Bradford, BD9 6RJ, United Kingdom
-
Investigational Site Number : 8260006
Oxford, Oxfordshire, OX3 9DU, United Kingdom
-
Newport Native MD- Site Number : 8400031
Newport Beach, California, 92663, United States
-
Northwell Health Physician Partners Rheumatology at Great Neck- Site Number : 8400028
Great Neck, New York, 11021, United States
-
Orlando ENT Associates - Orlando- Site Number : 8400008
Orlando, Florida, 32807, United States
-
Orso Health - Torrance - Hawthorne Boulevard- Site Number : 8400035
Torrance, California, 90505, United States
-
Ospedale Bellaria-Site Number: 3800009
Bologna, 40139, Italy
-
Paradisus Med Research - Miami- Site Number : 8400009
Miami, Florida, 33185, United States
-
SSM Health Saint Louis University Hospital- Site Number : 8400005
St Louis, Missouri, 63104, United States
-
Sacramento Ear Nose & Throat - Roseville- Site Number : 8400064
Roseville, California, 95661, United States
-
Sensa Health- Site Number : 8400038
Los Angeles, California, 90006, United States
-
TEN20 Clinical Research - Dallas- Site Number : 8400015
Dallas, Texas, 75244, United States
-
Treasure Valley Medical Research- Site Number : 8400063
Boise, Idaho, 83706, United States
-
University of Chicago Medical Center- Site Number : 8400018
Chicago, Illinois, 60637, United States
-
University of Southern California (USC) / Keck Medicine of USC- Site Number : 8400037
Arcadia, California, 91006, United States
Conditions
Explore the condition pages connected to this study.