Tiny implant shows promise for glaucoma control during cataract surgery
NCT ID NCT05062668
First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 1 time
Summary
This study looked at whether placing a tiny device called iStent during cataract surgery helps lower eye pressure in people with primary open-angle glaucoma. Researchers compared 80 patients who got the implant plus cataract surgery to those who had cataract surgery alone. The goal was to see if the implant safely improves pressure control over one year.
What this could mean
Our plain-language read of the trial. This is informational only, not medical advice or a prediction.
- Active substance
- iStent inject or inject W implant
- What this could lead to
- If successful, this could offer a safer way to lower eye pressure in glaucoma patients during cataract surgery, reducing the need for eye drops or more invasive surgery.
- What could go wrong
- This is a small, completed observational study, not a large randomized trial. The implant may not lower pressure enough for all patients, and long-term benefits or risks are not fully known.
This is an AI summary of the original study and may miss details. Read our disclaimer.
Study facts
What this study's own registry entry says, in plain language.
- Participants
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80 people
The number who actually took part.
- Started
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Sep 2021
- Finished
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Sep 2022
- Lead sponsor
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Other sponsor
The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.
Who can take part
This study's own entry requirements. Only the study team can say for certain whether you qualify.
Who is studied
There are two groups, the first group is the iStent group. The investigators took all the POAG patients operated at the CHU of Amiens or the CH of Saint-Quentin of a combined cataract and iStent inject or inject W surgery from January 2018 to September 2020. The second group is the control group of POAG patients operated only on cataract during the same period.
- Ages
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18 years and older
- Sex
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Anyone
- Healthy volunteers
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Not accepted
This study is not open to healthy volunteers. The entry requirements below say who it is open to.
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Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.
Inclusion Criteria: * patient who have undergone combined phacoemulsification surgery and insertion of at least one iStent® for chronic open-angle glaucoma in the ophthalmology department of the Amiens University Hospital or the Saint-Quentin University Hospital (iStent® group). * patient who have undergone simple phacoemulsification surgery in a patient with chronic open-angle glaucoma in the ophthalmology department of the Amiens University Hospital (control group). * patient with Chronic open-angle glaucoma confirmed by gonioscopic examination, visual field, optical coherence tomography of the optic nerve, fundus examination, pachymetry and intraocular air pressure and/or applanation. Exclusion Criteria: * acute angle closure glaucoma, * chronic angle closure glaucoma, * uveitic glaucoma, * traumatic glaucoma, * exfoliative glaucoma. * Previous filtering surgery on the operated eye. * Intraoperative complication.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
-
CHU Amiens Nord
Amiens, 80054, France
More trials for these conditions
Other studies related to the condition(s) this trial covers.