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New drug aims to treat deadly heart shock

NCT ID NCT07583446

First seen May 14, 2026 · Last updated Jun 21, 2026 · Updated 8 times

Summary

This study tests if the drug istaroxime can help people with mild to moderate cardiogenic shock caused by acute heart failure. About 600 adults will receive either istaroxime or a placebo through an IV for 48 hours. Researchers will check if it improves blood pressure, breathing, and reduces the risk of death or other serious events.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

istaroxime

What this could lead to

If it works, this could provide a new treatment to stabilize blood pressure and reduce complications in people with cardiogenic shock.

What could go wrong

This is an early-to-mid-stage trial with 600 participants. The drug may not improve outcomes or could cause side effects. Results may not apply to all patients.

Conditions

The condition(s) this trial relates to.

cardiogenic shock Shock, Cardiogenic

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.