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Simple squeeze exercise may ease arthritis pain, study hints
NCT ID NCT07665086
First seen Jun 27, 2026 · Last updated Jul 01, 2026 · Updated 2 times
Summary
This study tests whether a simple isometric (static) hand exercise can change how people with rheumatoid arthritis feel pain. Researchers will measure pain tolerance, pressure thresholds, and muscle oxygen levels in 66 adults. The goal is to see if this type of exercise can help the body's natural pain-modulation system work better.
What this could mean
Our plain-language read of the trial. This is informational only, not medical advice or a prediction.
- Active substance
- isometric exercise
- What this could lead to
- If successful, this could show that simple isometric exercises help manage pain in rheumatoid arthritis, pointing toward a non-drug pain relief strategy.
- What could go wrong
- This is a small, early-stage study (66 people) looking at immediate effects only. Results may not apply to all RA patients or lead to long-term benefits.
This is an AI summary of the original study and may miss details. Read our disclaimer.
Study facts
What this study's own registry entry says, in plain language.
- Phase
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Not a phased trial
Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.
- Participants
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About 66 people
The number the study aims to enrol. It can still change while the study runs.
- Started
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Dec 2025
- Expected to finish
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Dec 2027
An estimate. End dates often move.
- Lead sponsor
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Other sponsor
The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.
Who can take part
This study's own entry requirements. Only the study team can say for certain whether you qualify.
- Ages
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18 to 65 years
- Sex
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Anyone
- Healthy volunteers
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Not accepted
This study is not open to healthy volunteers. The entry requirements below say who it is open to.
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Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.
Inclusion Criteria: * Eligibility Criteria: * Diagnosis of rheumatoid arthritis * Being between 18-65 years of age * Volunteering to participate in the study Exclusion Criteria: * Having a neurological disease * Having pulmonary or cardiovascular problems that may affect daily living activities * Sensory system disorders * Previous upper extremity surgery * Having cognitive impairment * Having an accompanying rheumatic disease * Fracture, dislocation, or surgical intervention in the hand/wrist region within the last 6 months * Communication limitations that prevent following the study protocol * Having an exercise history in the last six months
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
How to take part
Only the study team decides who joins. These are the ways to reach them.
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The places running it
1 site. The list below names each one and where it is.
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The official record
The full official record for this study. This one lists no contact details, but it is the first place any would appear.
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A doctor treating you
A doctor who knows your case can contact a study site on your behalf, and can tell you whether this study is worth pursuing at all.
Contacts and locations
Locations
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Pamukkale University
Denizli, Turkey (Türkiye)
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