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New drug duo aims to stop smoldering myeloma from becoming full-blown cancer

NCT ID NCT02960555

First seen Nov 01, 2025 · Last updated Jun 17, 2026 · Updated 35 times

Summary

This study tests whether the drug isatuximab, given alone or with lenalidomide, can control or shrink the signs of smoldering multiple myeloma in people at high risk of developing active disease. About 61 participants receive the treatment to see if it delays progression and improves outcomes. The goal is to manage the condition and prevent it from worsening.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Locations

  • M D Anderson Cancer Center

    Houston, Texas, 77030, United States

  • Memorial Sloan Kettering Cancer Center

    New York, New York, 10065, United States

  • Mount Sinai Hospital

    New York, New York, 10029, United States

Conditions

The condition(s) this trial relates to.

Smoldering Multiple Myeloma smoldering plasma cell myeloma

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.