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New combo therapy shows promise for tough liver cancers

NCT ID NCT03655002

First seen May 16, 2026 · Last updated May 23, 2026 · Updated 2 times

Summary

This early-phase trial tests a new drug combination (IRX-2, cyclophosphamide, and nivolumab) in 8 adults with advanced liver cancer that has returned or spread and no longer responds to standard treatments. The goal is to find the safest dose and check for side effects. The approach aims to boost the immune system to fight the cancer more effectively.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Locations

  • City of Hope Medical Center

    Duarte, California, 91010, United States

  • HonorHealth Research Institute

    Scottsdale, Arizona, 85258, United States

  • Texas Oncology at Baylor Charles A Sammons Cancer Center

    Dallas, Texas, 75246, United States

Conditions

Explore the condition pages connected to this study.