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Genetic test fine-tunes chemo decisions for early breast cancer

NCT ID NCT03961880

First seen Nov 01, 2025 · Last updated Apr 29, 2026 · Updated 21 times

Summary

This study involved 270 women with early-stage, hormone-receptor-positive, HER2-negative breast cancer. Researchers wanted to see how a genetic test called Oncotype DX, which gives a Recurrence Score, influences whether doctors recommend chemotherapy. They also checked if the score relates to finding cancer cells in the bone marrow. The goal was to better understand how to personalize treatment and avoid unnecessary chemo.

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Contacts and locations

Locations

  • Department for Women's Health

    Tübingen, Baden-Wurttemberg, 72086, Germany

Conditions

Explore the condition pages connected to this study.