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Anesthesia choice may influence bone healing marker

NCT ID NCT07324681

Knowledge-focused Sponsor: Ankara City Hospital Bilkent Source: ClinicalTrials.gov ↗

What the study statuses mean

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Recruitment status, easiest to join first

Recruiting now
This trial is taking on new participants right now.
Not yet recruiting This study
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This study compares two types of anesthesia—general anesthesia and a nerve block—in 90 adults having forearm fracture surgery. Researchers will measure blood levels of irisin, a hormone linked to inflammation and healing, before and after surgery. The goal is to see if the type of anesthesia affects irisin levels and whether those changes relate to how well the bone heals.

What this could mean

Our plain-language read of the trial. This is informational only, not medical advice or a prediction.

What this could lead to
If successful, this could help doctors understand how anesthesia type affects healing after bone fracture surgery.
What could go wrong
This is a small, early-stage study that only measures a blood marker, not a treatment. It may not lead to any change in patient care.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Phase

Not a phased trial

Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.

Participants

About 90 people

The number the study aims to enrol. It can still change while the study runs.

Expected to start

Jan 2026

An estimate. Start dates often move.

Expected to finish

May 2026

An estimate. End dates often move.

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Ages

18 to 65 years

Sex

Anyone

Healthy volunteers

Not accepted

This study is not open to healthy volunteers. The entry requirements below say who it is open to.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: * Adults aged 18 to 65 years Scheduled for elective forearm fracture surgery Planned to receive either general anesthesia or infraclavicular brachial plexus block American Society of Anesthesiologists (ASA) physical status I-III Able to provide written and verbal informed consent Exclusion Criteria: * Age \<18 years or \>65 years Emergency surgery Refusal or inability to provide informed consent ASA physical status IV or V Known bone diseases or metabolic bone disorders Multiple trauma or associated organ injury Inability to mobilize Morbid obesity (BMI \>40 kg/m²) Renal failure Hepatic failure Neurological deficits or sequelae Contraindication or allergy to any anesthetic agents used in the study

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Conditions

The condition(s) this trial relates to.

inflammatory disease

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Angiogenesis Healing Inflamation

How to take part

Only the study team decides who joins. These are the ways to reach them.

  1. The official record

    ClinicalTrials.gov lists the study team's own contact details, including names and phone numbers. We don't republish those.

    Open the record ↗

  2. A doctor treating you

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