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New hope for deadly lung crisis: experimental combo therapy tested

NCT ID NCT03286556

Summary

This study tested a new combination treatment for patients experiencing a sudden, life-threatening worsening of their lung scarring disease (idiopathic pulmonary fibrosis). Researchers compared an intensive regimen of plasma exchange, the drug rituximab, and immunoglobulin infusions against standard steroid treatment. The goal was to see if reducing harmful antibodies in the blood could improve survival and breathing in these critically ill patients.

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Contacts and locations

Locations

  • Baylor University Medical Center

    Houston, Texas, 77030, United States

  • Dan Dilling

    Chicago, Illinois, 60611, United States

  • Temple University Hospital

    Philadelphia, Pennsylvania, 19140, United States

  • Thomas Jefferson University Medical Center

    Philadelphia, Pennsylvania, 19107, United States

  • University of Alabama at Birmingham

    Birmingham, Alabama, 35233, United States

  • University of Pittsburgh Medical Center

    Pittsburgh, Pennsylvania, 15213, United States

  • University of Utah Medical Center

    Salt Lake City, Utah, 84112, United States

Conditions

Explore the condition pages connected to this study.