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New injection after liver ablation may stop colorectal cancer spread

NCT ID NCT07321847

First seen Jan 11, 2026 · Last updated May 22, 2026 · Updated 22 times

Summary

This study tests whether an injectable drug called IP-001, given right after standard heat-based liver tumor ablation, can help prevent colorectal cancer from coming back in the liver or spreading elsewhere. About 717 adults with colorectal cancer that has spread only to the liver will be randomly assigned to receive either ablation alone or ablation plus a low or high dose of IP-001. The goal is to see if the drug can activate the immune system to fight any remaining cancer cells and improve long-term outcomes.

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