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First human trial tests new drug for rare, fatal brain disease

NCT ID NCT06153966

Recruiting now Disease control Sponsor: Ionis Pharmaceuticals, Inc. Source: ClinicalTrials.gov ↗

Summary

This early-stage study is testing a new drug called ION717 for people with prion disease, a rare and fatal brain condition. The drug is injected into the spinal fluid to try to lower the harmful protein that causes the disease. Researchers will check if the treatment is safe and how it affects the body and disease over several years.

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes NO responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • Fondazione I.R.C.C.S. Istituto Neurologico Carlo Besta

    ACTIVE_NOT_RECRUITING

    Milan, 20133, Italy

  • Hospital Clinic De Barcelona

    ACTIVE_NOT_RECRUITING

    Barcelona, 08036, Spain

  • Hôpital Universitaire Pitié Salpêtrière

    ACTIVE_NOT_RECRUITING

    Paris, 75013, France

  • Massachusetts General Hospital

    ACTIVE_NOT_RECRUITING

    Boston, Massachusetts, 02114, United States

  • McGill University Health Centre

    ACTIVE_NOT_RECRUITING

    Montreal, Quebec, H3A 2B4, Canada

  • Mihara Memorial Hospital

    ACTIVE_NOT_RECRUITING

    Gunma, Isesaki-shi, 372-0006, Japan

  • NYU Langone Health

    ACTIVE_NOT_RECRUITING

    New York, New York, 10016, United States

  • National Center of Neurology and Psychiatry

    RECRUITING

    Tokyo, Kodaira-shi, 187-8551, Japan

  • Neuromuscular Center Yoshimizu Hospital

    RECRUITING

    Yamaguchi, Shimonoseki-shi, 751-0826, Japan

  • Royal Melbourne Hospital

    ACTIVE_NOT_RECRUITING

    Parkville, 3050, Australia

  • Tel Aviv Sourasky Medical Center

    RECRUITING

    Tel Aviv, 6423906, Israel

  • University Hospitals Cleveland Medical Center

    RECRUITING

    Cleveland, Ohio, 44106, United States

  • University Medical Center Göttingen

    ACTIVE_NOT_RECRUITING

    Göttingen, 37075, Germany

Conditions

Explore the condition pages connected to this study.

PRION DISEASE