Three-Minute muscle relaxant timing may improve breathing tube placement in obese women
NCT ID NCT04808440
First seen Jun 26, 2026 · Last updated Jun 26, 2026
Summary
This study looked at whether waiting exactly three minutes after giving the muscle relaxant atracurium leads to better conditions for placing a breathing tube in obese women having gynecological surgery. One hundred adult female patients took part. Researchers rated intubation based on how easy the laryngoscopy was, vocal cord position, and coughing or movement during tube insertion.
What this could mean
Our plain-language read of the trial. This is informational only, not medical advice or a prediction.
- Active substance
- atracurium (a muscle relaxant)
- What this could lead to
- If successful, this could help anesthesiologists time muscle relaxants better for safer intubation in obese women.
- What could go wrong
- This is a small, completed study with only 100 participants, so results may not apply to all patients or settings. It does not test long-term outcomes.
This is an AI summary of the original study and may miss details. Read our disclaimer.
Study facts
What this study's own registry entry says, in plain language.
- Participants
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100 people
The number who actually took part.
- Started
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Mar 2021
- Finished
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Sep 2021
- Lead sponsor
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Other sponsor
The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.
Who can take part
This study's own entry requirements. Only the study team can say for certain whether you qualify.
Who is studied
Adults, no morbid obesity female patients, without risk factors for difficult tracheal intubation (ref IOT difficile) scheduled for gynaecologic surgery were prospectively included in this observational and monocentric study.
- Ages
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18 years and older
- Sex
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Female participants only
- Healthy volunteers
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Not accepted
This study is not open to healthy volunteers. The entry requirements below say who it is open to.
Show the full entry requirements Hide the full entry requirements
Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.
Inclusion Criteria: * Adult female * Patient to undergo general anesthesia with intubation for scheduled gynecological surgery * Patient informed about the study and not opposed to it Exclusion Criteria: * Patients with severe and morbid obesity (BMI\>35kg/m2) * Pregnancy * Patients with difficult intubation * Allergy to atracurium and to any other drug used. * Patient under tutorship / curatorship * Not affiliated with social insurance * Patient with AME
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
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Service Anesthésie Réanimation Chirurgicale Hôpital Cochin
Paris, 75014, France