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Can a simple uterine flush boost IVF pregnancy rates?

NCT ID NCT06684951

Knowledge-focused Sponsor: Omayma Ismail Khalaf Source: ClinicalTrials.gov ↗

What the study statuses mean

This study's is highlighted.

Recruitment status, easiest to join first

Recruiting now
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed This study
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jun 26, 2026 · Last updated Jun 26, 2026

Summary

This study looked at whether flushing the uterus with a low dose of the hormone hCG right after egg retrieval could improve pregnancy rates in women undergoing IVF. Researchers measured immune markers and blood flow in the uterus to see if the flush made the womb more receptive to an embryo. The trial involved 90 infertile women aged 18 to 40.

What this could mean

Our plain-language read of the trial. This is informational only, not medical advice or a prediction.

Active substance
human chorionic gonadotropin (hCG)
What this could lead to
If successful, this could point toward a simple way to improve IVF success rates by preparing the uterus for embryo implantation.
What could go wrong
This is a small, completed Phase 4 study with only 90 participants. The results may not apply to all women, and the intervention may not significantly improve pregnancy rates.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Phase

Phase 4

Runs after approval, following long-term safety and how well the treatment works in everyday use.

Participants

90 people

The number who actually took part.

Started

Oct 2022

Finished

Apr 2024

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Ages

18 to 40 years

Sex

Female participants only

Healthy volunteers

Not accepted

This study is not open to healthy volunteers. The entry requirements below say who it is open to.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: 1. The patient\'s consent to participate in the research study is crucial for data collection and analysis. 2. Each pair of individuals undergoing IVF/ICSI procedures typically possess grade 1 (G1) embryos during the embryo transfer process. 3. The age range of the female participants varied from 18 to 40 years. 4. Infertility arising from female factors, including issues like blocked fallopian tubes, lack of ovulation, and unexplained fertility challenges, was examined. 5. Male-related factors contributing to infertility were also taken into consideration. 6. The procedure involved the transfer of grade one embryos during a fresh cycle. Exclusion Criteria: Endometrioses, whether clinically suspected or discovered during laparoscopy, are of interest. 2\. Instances of congenital abnormalities in the reproductive system are being examined. 3\. Individuals above the age of forty are under consideration. 4. Individuals who do not possess G1 embryos are also included. 5. Patients with chronic systemic conditions (such as diabetes, hematologic disorders, hypertension, autoimmune disorders of the connective tissue, asthma, thyroid disorders) are a part of the study. 6\. The presence of empty follicles is noted in stimulated cycles where no oocytes were obtained during the aspiration procedure. \-

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Conditions

The condition(s) this trial relates to.

female infertility infertility disorder

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Female infertility

Contacts and locations

Locations

  • High Institute for Infertility Diagnosis and Assisted Reproductive Technology

    Baghdad, Iraq

More trials for these conditions

Other studies related to the condition(s) this trial covers.