Can lack of oxygen weaken your breathing muscles? new study investigates
NCT ID NCT06714435
First seen Jun 27, 2026 · Last updated Jun 27, 2026
Summary
This study looked at whether repeated low oxygen levels, like those seen in sleep apnea, can reduce the ability to keep breathing during effort. 28 healthy volunteers did a breathing test after 6 hours of normal air and after 6 hours of low oxygen. The goal is to understand if oxygen drops alone affect breathing endurance, which could help manage asthma attacks or respiratory infections.
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Study facts
What this study's own registry entry says, in plain language.
- Phase
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Not a phased trial
Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.
- Participants
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28 people
The number who actually took part.
- Started
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Jan 2025
- Finished
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Oct 2025
- Lead sponsor
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Other sponsor
The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.
Who can take part
This study's own entry requirements. Only the study team can say for certain whether you qualify.
- Ages
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25 to 40 years
- Sex
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Anyone
- Healthy volunteers
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Accepted
You do not need to have the condition being studied to take part.
Show the full entry requirements Hide the full entry requirements
Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.
Inclusion Criteria: * Non-excessive coffee drinker (\< 3 espressos / day) * Non-smoker or weaned for 3 months and total consumption \< 10 packs/year * With a BMI within \]18 - 25\[ kg/m². * Benefiting from a Social Security plan or benefiting from one through a third party * Giving free, informed and signed consent, after receiving clear and fair information about the study. Non-inclusion Criteria: * History of respiratory or ENT disease (asthma, chronic bronchitis, COPD, respiratory allergy, swallowing disorders, oropharyngeal malformation, obstructive or central sleep apnea-hypopnea syndrome, alveolar hypoventilation syndrome) * Respiratory, cardiovascular, muscular, neurological or diabetic pathology or disorders * Raynaud's disease/syndrome * History of epilepsy or history of malaise suggestive of epilepsy * Psychiatric history requiring hospitalization * Liver failure * Renal insufficiency * History of acute mountain sickness (presence during or after a stay at altitude of symptoms of vertigo, headache, nausea/vomiting and incapacitating fatigue: Lake Louise score \> 0) * History of migraines * Taking medications that interfere with respiratory function or cardiovascular function, or psychotropic drugs ( anxiolytic, sedative, antidepressant, neuroleptic, muscle relaxant, etc.). * Alcohol or drug dependence * Anemia, sickle-cell anemia * SpO2 \< 97% at rest in room air * Currently participating in another clinical study * Protected persons within the meaning of article L1121-5 to 8 (persons benefiting from enhanced protection, i.e. minors, persons deprived of their liberty by a judicial or administrative decision, pregnant or breast-feeding women, persons staying in a health or social establishment, adults under legal protection, and patients in emergency situations). - Women with childbearing capacity who do not have effective contraception (hormonal/mechanical: oral, injectable, transcutaneous, implantable, intrauterine device, or surgical: tubal ligation, hysterectomy, total oophorectomy). * Incidental finding of acute mountain sickness (Lake Louise score \>0) * Pregnant woman (incidental finding) * Persistence of average sleep time \< 6h * Non-reversible deterioration in volunteer's state of health within study period * Electroencephalogram signal unusable
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Genom att skicka in godkänner du våra Användarvillkor
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
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CHU Poitiers
Poitiers, France, 86000, France
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