Could a better toothbrush beat gum disease?
NCT ID NCT07575997
First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 1 time
Summary
This study compares a test interdental brush to other interdental brushes in 88 adults with active periodontal disease. Over 4 weeks, researchers will measure plaque, gum bleeding, and pocket depth to see which brush works best. Participants use the brush twice daily and report any side effects.
What this could mean
Our plain-language read of the trial. This is informational only, not medical advice or a prediction.
- Active substance
- interdental brush
- What this could lead to
- If successful, this could show that a particular interdental brush is better at controlling gum disease than others.
- What could go wrong
- This is a small, short-term exploratory study (88 people, 4 weeks). Results may not apply to everyone, and the benefit over regular brushes may be small.
This is an AI summary of the original study and may miss details. Read our disclaimer.
Study facts
What this study's own registry entry says, in plain language.
- Phase
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Not a phased trial
Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.
- Participants
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About 88 people
The number the study aims to enrol. It can still change while the study runs.
- Started
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Apr 2026
- Expected to finish
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Jun 2027
An estimate. End dates often move.
- Lead sponsor
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A company
The lead sponsor is a pharmaceutical, biotech, or medical-device company.
Who can take part
This study's own entry requirements. Only the study team can say for certain whether you qualify.
- Ages
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18 to 80 years
- Sex
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Anyone
- Healthy volunteers
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Not accepted
This study is not open to healthy volunteers. The entry requirements below say who it is open to.
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Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.
Inclusion Criteria: * Subject aged between 18 and 80 years included * Subject having signed his/her written informed consent for his/her participation in the study * Subject diagnosed with active generalized periodontal disease (excluding gingivitis) * Subject having at least 20 natural teeth (10 teeth on each side (right and left)) Non-inclusion criteria: * Subject unable to understand the information given including study procedures (for linguistic or psychiatric reasons) and to give his/her consent in writing and to report required information in a questionnaire * For woman of childbearing potential: pregnant or breastfeeding or planning to be pregnant during the study * Subject having any other oral condition than periodontal disease (ex: dermatologic ulcers), or any orthodontic conditions liable to interfere with the study assessment or considered by the investigator hazardous for the subject or incompatible with study requirements * Systemic treatment or topical treatment/product currently taken/applied in the mouth liable to interfere with study assessments according to the investigator or planned to be taken/applied during the study * Subject has received periodontal therapy (scaling, root planing, surgery, etc.) within 2 months before the inclusion * Subject who has undergone oral or gum surgery within 2 months before the inclusion, or planned to be performed during the study
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
How to take part
Only the study team decides who joins. These are the ways to reach them.
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The places running it
1 site. The list below names each one and where it is.
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The official record
ClinicalTrials.gov lists the study team's own contact details, including names and phone numbers. We don't republish those.
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A doctor treating you
A doctor who knows your case can contact a study site on your behalf, and can tell you whether this study is worth pursuing at all.
Contacts and locations
Locations
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Cliniques universitaires Saint-Luc
RECRUITINGBrussels, 1200, Belgium
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Other studies related to the condition(s) this trial covers.
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- Can a laser boost the power of gum surgery?
- Can a Two-Step mouthwash and toothpaste routine boost gum healing?
- Gum fluid proteins may hold clues to periodontal disease severity