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New Hand-Gesture therapy may help stroke survivors find words again

NCT ID NCT04267198

Symptom relief Sponsor: VA Office of Research and Development Source: ClinicalTrials.gov ↗

What the study statuses mean

This study's is highlighted.

Recruitment status, easiest to join first

Recruiting now
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed This study
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study tested a behavioral therapy called Intention Treatment for Anomia in 32 stroke survivors with aphasia (language impairment). The therapy uses a left-hand circular gesture to engage the brain's intention mechanisms and improve word retrieval. Researchers looked at how often the therapy should be given and what factors predict a good response, aiming to make treatment more effective and personalized.

What this could mean

Our plain-language read of the trial. This is informational only, not medical advice or a prediction.

Active substance
Intention Treatment for Anomia (a behavioral therapy using a left-hand circular gesture to aid word retrieval)
What this could lead to
If successful, this could help personalize aphasia therapy, improving word-finding ability for stroke survivors.
What could go wrong
This is a small, completed study (32 participants) focused on understanding treatment effects and predictors, not a large-scale efficacy trial. Results may not apply to all people with aphasia.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Phase

Not a phased trial

Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.

Participants

32 people

The number who actually took part.

Started

May 2021

Finished

Sep 2025

Lead sponsor

A government agency

The lead sponsor is a US federal agency other than the NIH.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Ages

21 to 89 years

Sex

Anyone

Healthy volunteers

Not accepted

This study is not open to healthy volunteers. The entry requirements below say who it is open to.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: * English as primary language * \> 6 months post-onset a left-hemisphere stroke. Multiple strokes are acceptable as long as they are confined to the left hemisphere. * Diagnosis of aphasia * Presence of word retrieval deficits * Adequate comprehension as judged by ability to complete two-step commands on the Western Aphasia Battery. Exclusion Criteria: * Severe apraxia of speech or dysarthria * Clinically significant depression * For MRI safety: implanted medical devices, metal in the body and claustrophobia.

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Conditions

The condition(s) this trial relates to.

aphasia Language stroke disorder

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Aphasia Stroke

Contacts and locations

Locations

  • Atlanta VA Medical and Rehab Center, Decatur, GA

    Decatur, Georgia, 30033-4004, United States

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