Can herbs and spinal manipulation ease chronic back pain? new study investigates
NCT ID NCT03879447
First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 2 times
Summary
This study looks at whether a combination of herbal medicine and Chuna manual therapy (a Korean spinal manipulation technique) can safely reduce pain and improve walking ability in people with low back pain or sciatica caused by lumbar spinal stenosis or spondylolisthesis. Researchers will follow 110 patients for 4 months, tracking pain levels, disability, and quality of life. Because this is an observational study without a control group, it can suggest but not prove whether the treatment works.
What this could mean
Our plain-language read of the trial. This is informational only, not medical advice or a prediction.
- Active substance
- Herbal medicine (a mix of 12 herbs) and Chuna manual spinal manipulation
- What this could lead to
- If it works, this could point toward a non-surgical option for managing chronic back and leg pain caused by spinal narrowing or slippage.
- What could go wrong
- This is an early observational study with only 110 participants and no comparison group, so results may not prove effectiveness. Herbal medicines can also cause side effects or interact with other drugs.
This is an AI summary of the original study and may miss details. Read our disclaimer.
Study facts
What this study's own registry entry says, in plain language.
- Participants
-
110 people
The number who actually took part.
- Started
-
Jun 2019
- Expected to finish
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Dec 2027
An estimate. End dates often move.
- Lead sponsor
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Other sponsor
The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.
Who can take part
This study's own entry requirements. Only the study team can say for certain whether you qualify.
Who is studied
Lumbar stenosis or lumbar spondylolisthesis
- Ages
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19 to 75 years
- Sex
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Anyone
- Healthy volunteers
-
Not accepted
This study is not open to healthy volunteers. The entry requirements below say who it is open to.
Show the full entry requirements Hide the full entry requirements
Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.
Inclusion Criteria: * Patients with radiating leg pain or low back pain (LBP) intensity of NRS ≥5 * Patients diagnosed with lumbar stenosis based on dural sac cross-sectional area (DSCA) of \<100 mm2 or morphological grading ≥B as assessed on MRI; or patients diagnosed with lumbar spondylolisthesis based on Meyerding Grade Ⅱ or higher as assessed on X-ray * Clear neurogenic claudication symptoms (symptoms aggravated with walking, and alleviated upon resting in lumbar flexion position), if lumbar stenosis patient * Patients with plans of receiving Korean medicine treatment for lumbar spinal stenosis for ≥4 months * Patients who have agreed to study participation Exclusion Criteria: * Patients with vascular claudication * Patients with other systemic diseases that may interfere with treatment effect or outcome interpretation * Patients with soft tissue pathologies or pathologies of non-spinal origin that may cause LBP or radiating leg pain (e.g. spinal tumor, rheumatoid arthritis) * Patients for whom acupuncture treatment may be inappropriate or unsafe (e.g. hemorrhagic diseases, blood clotting disorders, history of anti-coagulation medicine intake, serious diabetes with risk of infection, severe cardiovascular diseases, or other conditions deemed unsuitable for acupuncture treatment) * Patients with medical history of spinal surgery within the past 3 months * Patients who were treated with invasive interventions such as Korean medicine treatment, injections, physical therapy, or with medicine that may potentially influence pain such as NSAIDs (nonsteroidal antiinflammatory drugs) within the past week * Pregnant patients or patients planning pregnancy * Patients with serious psychological disorders * Previous participation in other clinical studies within 1 month of current study enrollment, or plans to participate in other clinical studies during participation (including follow-up period) of the current study after study enrollment * Patients unable to fill out study participation consent form * Patients deemed unsuitable for study participation as assessed by the researchers
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
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Jaseng Medical Foundation
Seoul, South Korea
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Other studies related to the condition(s) this trial covers.
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