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Less insulin may be just as effective for high potassium

NCT ID NCT06036823

Disease control Sponsor: Oman Medical Speciality Board Source: ClinicalTrials.gov ↗

What the study statuses mean

This study's is highlighted.

Recruitment status, easiest to join first

Recruiting now
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed This study
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study tested whether 5 units of insulin works as well as 10 units for lowering dangerously high potassium levels in adults. Researchers measured potassium levels two hours after treatment in 384 participants. The goal is to find a dose that is effective but reduces the risk of low blood sugar, a common side effect of insulin.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Phase

Phase 4

Runs after approval, following long-term safety and how well the treatment works in everyday use.

Participants

384 people

The number who actually took part.

Started

Oct 2023

Finished

Sep 2025

Lead sponsor

A government agency

The lead sponsor is a government body.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Ages

18 years and older

Sex

Anyone

Healthy volunteers

Not accepted

This study is not open to healthy volunteers. The entry requirements below say who it is open to.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: * Hyperkalemia patients with lab potassium levels equal to or more than 5.5 mEq/L (≥ 5.5 mEq/L)+. * Adult: age 18 years or more. * Agreed to participate in the study. * If an investigator decides to start anti-hyperkalemia medications based on the VBG/ABG patient can be enrolled but if the main laboratory value is less than 5.5 mEq/L patients will be excluded Exclusion Criteria: * Cardiac arrest * Hyperglycemia with random blood sugar 20 mmol/L (13) or with acute diabetic complications like Diabetic Ketoacidosis / Hyperosmolar Hyperglycemic State. * Hypoglycemia with random blood sugar (RBS) ≤ 3.89 mmol/l in Diabetic patients and less than 3 mmol/l in non-diabetic patients. * Allergies for any medication in the protocol. * Pregnancy. * Hemolyzed potassium level as reported by the main lab. * Hemolysis, Tumor lysis syndrome, or Rhabdomyolysis due to the ongoing release of potassium. * Acidosis with a pH less than 7.1 will require Sodium bicarbonate (NaHO3). * A patient who will need urgent Furosemide (Lasix), and or dialysis during the study period of 2 hours. * Refused to participate.

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Conditions

The condition(s) this trial relates to.

Hyperkalemia Insulin Resistance

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Electrolyte disturbance Electrolyte imbalance Hyperkalemia Potassium imbalance

Contacts and locations

Locations

  • Sultan Qaboos University hospital

    Seeb, Muḩāfaz̧at Masqaţ, 123, Oman

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