Den här översättningen är inte klar ännu. Den här sidan är just nu på engelska.

Gå till den engelska sidan

Cure My Disease

Don't miss your cure!

 Log in / Sign up

Can a custom breathing workout help patients leave the ventilator faster?

NCT ID NCT07761468

Disease control Sponsor: Hospital H+ Queretaro Source: ClinicalTrials.gov ↗

What the study statuses mean

This study's is highlighted.

Recruitment status, easiest to join first

Recruiting now
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only This study
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Aug 12, 2026 · Last updated Aug 13, 2026 · Updated 1 time

Summary

This trial tests whether a specific daily 'dose' of inspiratory muscle training can strengthen the breathing muscles of adults on mechanical ventilation in the ICU. Patients are assigned to one of three training intensities, calculated using a new formula called the Total Inspiratory Work Unit (UTIT), and adjusted daily based on their breathing strength. The goal is to see which dose best improves muscle strength and reduces the total time spent on the ventilator.

What this could mean

Our plain-language read of the trial. This is informational only, not medical advice or a prediction.

Active substance
Inspiratory muscle training using a POWERbreathe K5 device, with daily dose calculated by the Total Inspiratory Work Unit (UTIT) formula.
What this could lead to
If successful, this could establish a standardized, optimal dose of breathing-muscle training for ICU patients, potentially shortening time on ventilators and speeding recovery.
What could go wrong
This is a small, early-phase trial (60 patients) testing three doses, so results may not apply broadly. Training may not improve outcomes for all patients, and there is a risk of muscle fatigue or discomfort.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Phase

Not a phased trial

Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.

Participants

About 60 people

The number the study aims to enrol. It can still change while the study runs.

Started

Aug 2025

Expected to finish

Nov 2026

An estimate. End dates often move.

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Ages

18 years and older

Sex

Anyone

Healthy volunteers

Not accepted

This study is not open to healthy volunteers. The entry requirements below say who it is open to.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: * Adult patients (\>18 years of age) admitted to the Intensive Care Unit (ICU). * Invasive mechanical ventilation support for more than 48-72 hours. * Hemodynamic stability (defined as absence of vasopressors or receiving stable doses). * Adequate oxygenation and ventilatory parameters: PEEP \< 10 cmH2O, FiO2 \< 0.6, and PaO2/FiO2 ratio \> 150-200. * Ability to cooperate with instructions or absence of deep sedation. Exclusion Criteria: * Pre-existing neuromuscular pathology directly affecting respiratory muscles. * Severe thoracic trauma or recent thoracic surgery. * Unresolved pneumothorax or bronchopleural fistula. * Severe hemodynamic instability or severe cardiac arrhythmias. * Level of sedation that prevents active participation in sessions. * Pregnancy

Get updates

Get notified about this study

Sign up to get updates when this study changes or when new studies for Mechanical ventilation weaning are added.

Vår säkerhetsrekommendation!

Genom att skicka in godkänner du våra Användarvillkor

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Mechanical ventilation weaning Respiratory muscle weakness Ventilator-induced diaphragm dysfunction

How to take part

Only the study team decides who joins. These are the ways to reach them.

  1. The places running it

    1 site. The list below names each one and where it is.

  2. The official record

    The full official record for this study. This one lists no contact details, but it is the first place any would appear.

    Open the record ↗

  3. A doctor treating you

    A doctor who knows your case can contact a study site on your behalf, and can tell you whether this study is worth pursuing at all.

Contacts and locations

Locations

  • Hospital H+ Querétaro, Santiago de Querétaro, Querétaro

    Querétaro City, Querétaro, 76000, Mexico

More trials for these conditions

Other studies related to the condition(s) this trial covers.