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Can a blood injection thicken gums around implants? new trial aims to find out

NCT ID NCT06753396

Disease control Sponsor: Kutahya Health Sciences University Source: ClinicalTrials.gov ↗

What the study statuses mean

This study's is highlighted.

Recruitment status, easiest to join first

Recruiting now This study
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jun 26, 2026 · Last updated Jun 26, 2026

Summary

This study tests whether injecting platelet-rich fibrin (a substance made from the patient's own blood) into the gums around dental implants can make the gums thicker and healthier. It includes 80 adults with thin gums around their implants. The injection is given three times over three months, and the researchers will measure gum thickness and appearance after one year.

What this could mean

Our plain-language read of the trial. This is informational only, not medical advice or a prediction.

Active substance
injectable platelet-rich fibrin
What this could lead to
If it works, this could offer a simple way to thicken gums around dental implants, reducing the risk of infection and bone loss.
What could go wrong
This is a small, early-stage study with no control group, so results may not be conclusive. The procedure is repeated three times and may not work for everyone.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Phase

Not a phased trial

Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.

Participants

About 80 people

The number the study aims to enrol. It can still change while the study runs.

Started

Dec 2022

Expected to finish

Apr 2026

An estimate. End dates often move.

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Ages

18 years and older

Sex

Anyone

Healthy volunteers

Not accepted

This study is not open to healthy volunteers. The entry requirements below say who it is open to.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: 1. be over 18 years old 2. The patient does not have any systemic disease 3. Patients who do not smoke or who smoke less than 10 cigarettes 4. Peri-implant keratinized mucosa width less than 2 mm 5. Peri-implant mucosal thickness less than 2 mm Exclusion Criteria: 1. Being out of the defined age group 2. Any systematic contraindication for periodontal surgery 3. Patients who smoke more than 10 cigarettes per day 4. Patients with adequate peri-implant keratinized mucosa width and mucosal thickness 5. Pregnancy 6. Patients taking medication that suppresses the immune system or impairs healing 7. Patients taking medication that impairs the bleeding condition

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As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Peri-implant tissues

How to take part

Only the study team decides who joins. These are the ways to reach them.

  1. The places running it

    1 site. The list below names each one and where it is.

  2. The official record

    ClinicalTrials.gov lists the study team's own contact details, including names and phone numbers. We don't republish those.

    Open the record ↗

  3. A doctor treating you

    A doctor who knows your case can contact a study site on your behalf, and can tell you whether this study is worth pursuing at all.

Contacts and locations

Locations

  • Kütahya Health Sciences University Faculty of Dentistry

    RECRUITING

    Kütahya, 43100, Turkey (Türkiye)

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