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Can lung cancer run in families? new study investigates genetic risk

NCT ID NCT01754025

First seen Jan 06, 2026 · Last updated May 01, 2026 · Updated 16 times

Summary

This study looks at whether certain inherited gene changes (EGFR mutations) increase the risk of lung cancer, especially in people who never smoked. Researchers collect saliva from cancer patients with a specific tumor mutation (T790M) to see if they carry an inherited mutation. Close relatives can also join to help understand how these mutations affect cancer risk. The goal is to learn more about hereditary patterns, not to test a treatment.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Locations

  • Dana-Farber Cancer Institute

    Boston, Massachusetts, 02215, United States

  • Vanderbilt-Ingram Cancer Center

    Nashville, Tennessee, 37232, United States

Conditions

Explore the condition pages connected to this study.