New inhaled sedative could replace standard IV drug in ICU
NCT ID NCT05312385
First seen Apr 15, 2026 · Last updated May 19, 2026 · Updated 6 times
Summary
This study tested whether an inhaled sedative (isoflurane) works as well as a common IV sedative (propofol) for keeping ICU patients calm while on a breathing machine. About 277 adults who needed sedation for more than 12 hours took part. The goal was to see if the inhaled method keeps patients at the right sedation level without needing extra rescue medication.
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the original study
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Contacts and locations
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Locations
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Emory University
Atlanta, Georgia, 30322, United States
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Houston Methodist Hospital
Houston, Texas, 77030, United States
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Intermountain Health Care Health Services
Salt Lake City, Utah, 84111, United States
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MD Anderson Cancer Center
Houston, Texas, 77030, United States
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Mayo Clinic
Rochester, Minnesota, 55905, United States
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The Brigham and Women´s Hospital
Boston, Massachusetts, 02115, United States
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The Cleveland Clinic Foundation
Cleveland, Ohio, 44195, United States
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Tufts Medical Center
Boston, Massachusetts, 02111, United States
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University of Chicago
Chicago, Illinois, 60637, United States
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University of Cincinnati
Cincinnati, Ohio, 45219, United States
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University of Colorado Anschutz Medical Campus
Aurora, Colorado, 80045, United States
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University of Texas Southwestern Medical Center
Dallas, Texas, 75390, United States
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University of Virginia
Charlottesville, Virginia, 22903, United States
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Vanderbilt University Medical Center
Nashville, Tennessee, 37232, United States
Conditions
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