Daily inhaler trial aims to slow genetic lung damage
NCT ID NCT04204252
Summary
This study is testing whether inhaling a protein called AAT daily can slow down lung damage in adults with a genetic condition called Alpha-1 antitrypsin deficiency. For the first two years, half the participants will receive the active treatment and half will receive a placebo, followed by two years where everyone gets the active treatment. Researchers will measure lung function, scan lungs, and track symptoms to see if the treatment helps preserve breathing ability.
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Contacts and locations
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Study contacts
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Contact
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Locations
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Beaumont Hospital
RECRUITINGDublin, D09 YD60, Ireland
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Canisius Wilhelmina Hospital (CWZ)
RECRUITINGNijmegen, 6532SZ, Netherlands
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Leiden University Medical Center (LUMC)
RECRUITINGLeiden, ZA, 2333ZA, Netherlands
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Royal Infirmary of Edinburgh
RECRUITINGEdinburgh, EH16 4SA, United Kingdom
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Skåne University Hospital
RECRUITINGMalmo, SE-20502, Sweden
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Tays Central Hospital
RECRUITINGTampere, Finland
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University Hospital (UZ) Leuven
RECRUITINGLeuven, Belgium
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University Hospital Southampton NHS Foundation Trust
RECRUITINGSouthampton, SO16 6YD, United Kingdom
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University Hospitals Birmingham NHS Foundation Trust
RECRUITINGBirmingham, B15 2GW, United Kingdom
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Conditions
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