Daily inhaler tested to halt genetic lung disease progression
NCT ID NCT04204252
Summary
This study is testing whether inhaling a protein called Alpha-1 Antitrypsin (AAT) daily can slow down worsening lung function in people with a genetic condition called Alpha-1 Antitrypsin Deficiency. For the first two years, 220 participants will either receive the active inhaled treatment or a placebo (inactive substance) to compare results. The main goal is to see if this convenient inhaled treatment can protect the lungs better than no treatment, potentially offering a new way to manage this serious condition.
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Contacts and locations
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Study contacts
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Contact
Phone: •••-•••-•••• Email: •••••@•••••
Locations
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Beaumont Hospital
RECRUITINGDublin, D09 YD60, Ireland
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Canisius Wilhelmina Hospital (CWZ)
RECRUITINGNijmegen, 6532SZ, Netherlands
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Leiden University Medical Center (LUMC)
RECRUITINGLeiden, ZA, 2333ZA, Netherlands
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Royal Infirmary of Edinburgh
RECRUITINGEdinburgh, EH16 4SA, United Kingdom
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Skåne University Hospital
RECRUITINGMalmo, SE-20502, Sweden
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Tays Central Hospital
RECRUITINGTampere, Finland
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University Hospital (UZ) Leuven
RECRUITINGLeuven, Belgium
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University Hospital Southampton NHS Foundation Trust
RECRUITINGSouthampton, SO16 6YD, United Kingdom
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Contact Phone: •••-•••-•••• Email: •••••@•••••
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University Hospitals Birmingham NHS Foundation Trust
RECRUITINGBirmingham, B15 2GW, United Kingdom
Contact Phone: •••-•••-•••• Email: •••••@•••••
Contact Phone: •••-•••-•••• Email: •••••@•••••
Conditions
Explore the condition pages connected to this study.