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New hope for controlling debilitating side effect of powerful cancer drugs

NCT ID NCT04305145

Summary

This study is testing if a drug called infliximab is better than standard steroid treatment at resolving severe diarrhea and colon inflammation caused by immunotherapy drugs in people with advanced skin cancer. About 42 participants with stage III or IV skin cancer who develop this serious side effect will be randomly assigned to receive either infliximab or steroids for about 7 weeks. The main goal is to see which treatment helps more patients achieve resolution of their symptoms without needing ongoing steroids.

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Contacts and locations

Locations

  • Dana-Farber Cancer Institute

    Boston, Massachusetts, 02215, United States

  • Massachusetts General Hospital Cancer Center

    Boston, Massachusetts, 02114, United States

Conditions

Explore the condition pages connected to this study.