Immune-related adverse event

This study tests whether combining mycophenolate mofetil (MMF) with prednisone can better treat liver inflammation caused by checkpoint inhibitor cancer drugs. The trial includes adults with moderate to severe immune-related hepatitis who need to pause their cancer therapy. The m…

This study tests whether using inhaled budesonide (a steroid commonly used for asthma) for one year can stop lung inflammation from coming back in cancer patients who had a serious immune reaction to immunotherapy. About 94 adults with solid tumors who recently had lung inflammat…

This Phase 2 trial tests whether adding thymosin alpha 1 to the immunotherapy drug toripalimab can help elderly patients (60+) with advanced melanoma. The study will enroll 55 participants and measure how many patients' tumors shrink or disappear. Researchers also want to see if …

This trial tests whether vedolizumab, a drug that calms inflammation in the gut, can prevent diarrhea and colitis caused by immune checkpoint inhibitors. People with advanced melanoma, lung, or kidney cancer who are starting immunotherapy and show early signs of gut inflammation …

This study tests whether the drug adalimumab can help people with arthritis caused by cancer immunotherapy use less steroids. About 30 adults will be randomly assigned to receive either adalimumab or standard steroid treatment. The goal is to see if adalimumab can control arthrit…