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Spinal fluid inflammation may explain tethered cord damage in kids

NCT ID NCT07611058

Knowledge-focused Sponsor: University Hospital, Lille Source: ClinicalTrials.gov ↗

What the study statuses mean

This study's is highlighted.

Recruitment status, easiest to join first

Recruiting now
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed This study
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jun 24, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This study examined spinal fluid from 32 children with tethered spinal cord to see if inflammation plays a role in the condition. Researchers collected fluid samples during surgery and looked for markers of inflammation. The goal was to better understand how the spinal cord gets damaged, which could lead to new treatments in the future.

What this could mean

Our plain-language read of the trial. This is informational only, not medical advice or a prediction.

What this could lead to
If inflammation is found, it could point toward new ways to protect the spinal cord in children with tethered cord.
What could go wrong
This is a small, completed observational study that only looked for markers of inflammation. It does not test any treatment, so it may not lead to any direct benefit.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Phase

Not a phased trial

Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.

Participants

32 people

The number who actually took part.

Started

May 2024

Finished

Jan 2026

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Ages

Up to 17 years

Sex

Anyone

Healthy volunteers

Not accepted

This study is not open to healthy volunteers. The entry requirements below say who it is open to.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: * Infants and children under 18 years of age * Carriers of an attached marrow: lipomatous fiilum, meningocele, myelomeningocele, myelolipoma, * Consent of the child's parents, * Socially insured patient, * Patient willing to comply with all study procedures and duration, Exclusion Criteria: * Patients over 18 years of age, * Chronic inflammatory disease, * Ongoing anti-inflammatory treatments, * No parental consent,

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Conditions

The condition(s) this trial relates to.

Inflammation lipoma meningocele myelomeningocele tethered spinal cord syndrome

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Tethered spinal cord, including thickened filum, lipomas, myelomeningocele and meningocele

Contacts and locations

Locations

  • chu de Lille

    Lille, France