700 heart infection patients enrolled in landmark study to improve care
NCT ID NCT04992923
First seen Jun 27, 2026 · Last updated Jun 27, 2026
Summary
This study follows 700 patients with infective endocarditis, a serious heart infection, to gather real-world data on complications and outcomes. Researchers aim to improve treatment guidelines, which currently rely on expert opinion due to limited evidence. No new drug or treatment is being tested.
What this could mean
Our plain-language read of the trial. This is informational only, not medical advice or a prediction.
- What this could lead to
- If successful, this study could provide better guidelines for managing infective endocarditis and reducing its complications.
- What could go wrong
- This is an observational study, not a treatment trial. It cannot directly improve outcomes, and results may take years to influence practice.
This is an AI summary of the original study and may miss details. Read our disclaimer.
Study facts
What this study's own registry entry says, in plain language.
- Participants
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About 700 people
The number the study aims to enrol. It can still change while the study runs.
- Started
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Sep 2020
- Expected to finish
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Mar 2041
An estimate. End dates often move.
- Lead sponsor
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Other sponsor
The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.
Who can take part
This study's own entry requirements. Only the study team can say for certain whether you qualify.
Who is studied
All the patients with IE admitted at Cardiology institute of the Pitié-Salpêtrière hospital
- Ages
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18 years and older
- Sex
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Anyone
- Healthy volunteers
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Not accepted
This study is not open to healthy volunteers. The entry requirements below say who it is open to.
Show the full entry requirements Hide the full entry requirements
Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.
Inclusion Criteria: * Patients with confirmed IE according to European Society of Cardiology criteria Exclusion Criteria: * Opposition of the patient to participate
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Get notified about this study
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
How to take part
Only the study team decides who joins. These are the ways to reach them.
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The places running it
1 site. The list below names each one and where it is.
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The official record
ClinicalTrials.gov lists the study team's own contact details, including names and phone numbers. We don't republish those.
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A doctor treating you
A doctor who knows your case can contact a study site on your behalf, and can tell you whether this study is worth pursuing at all.
Contacts and locations
Locations
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APHP Pitié-Salpêtrière Hospital, Department of Cardiology
RECRUITINGParis, 75013, France
More trials for these conditions
Other studies related to the condition(s) this trial covers.
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- Could a simple dental cleaning prevent a deadly heart infection?
- Heart infection registry aims to unlock better treatments
- New diagnostic tool could speed up treatment for deadly heart infection
- New antibiotic strategy could shorten hospital stays for heart infections