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Can kids with allergies use nasal spray only when needed? new study investigates.

NCT ID NCT05299086

First seen Nov 18, 2025 · Last updated Jun 19, 2026 · Updated 29 times

Summary

This study looked at whether children with year-round allergic rhinitis can use a nasal steroid spray only when symptoms bother them, instead of every day. Sixty-eight children aged 6 to 18 were randomly assigned to either daily use or as-needed use of fluticasone furoate spray. The goal was to compare how well each approach controls nasal symptoms like sneezing, itching, runny nose, and congestion, and to see if as-needed use reduces side effects and total drug exposure.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Locations

  • Division of Allergy and Immunology, Department of Pediatrics, Faculty of Medicine Siriraj Hospital, Mahidol University

    Bangkok, Bangkok, 10700, Thailand

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

Fluticasone furoate nasal spray

What this could lead to

If it works, this could show that using the spray only when symptoms flare is just as effective as daily use, with fewer side effects and lower total drug exposure.

What could go wrong

This is a small, completed Phase 3 trial with only 68 children, so results may not apply to all kids. The as-needed approach might not control symptoms as well in more severe cases.

Conditions

The condition(s) this trial relates to.

CHILD syndrome perennial allergic rhinitis

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.